biostudies-literatureHuang XScience and technology project of Fuzhou Medical College of Nanchang UniversityJiangxi Province university humanities and social science research projectScience and Technology Research Project of Jiangxi Provincial Department of EducationProject supported by Jiangxi Science and Technology Support PlanScience and technology project of Jiangxi Provincial Administration of Traditional Chinese Medicinee090728https://www.ebi.ac.uk/biostudies/studies/S-EPMC11552014biostudies-literatureUnknown14(11)<h4>Introduction</h4>Lung cancer continues to be a common form of cancer worldwide and a primary contributor to cancer-related fatalities. Non-small cell lung cancer (NSCLC) is the most prevalent form, making up 80% to 85% of newly identified malignant lung tumours, and remains a major concern for worldwide health. Surgical resection is the preferred treatment for localised NSCLC, but more than one-third of patients present with locally advanced, unresectable tumours. Concurrent radiation therapy and chemotherapy are believed to offer the potential for prolonged disease-free and overall survival to those patients. However, the results are inconsistent, and systematic meta-analysis is lacking to evaluate its treatment effect comprehensively. Therefore, we will conduct a meta-analysis to evaBMJ openThree-dimensional conformal radiation therapy with concurrent chemotherapy for stage III non-small cell lung cancer: protocol for a systematic review and meta-analysis.PMC11552014JY21240FYKJ202404GJJ2089022022B110320133BBF60078Xu LLi WChen QHuang SZhu JHuang XRen YXu JfalseThree-dimensional conformal radiation therapy with concurrent chemotherapy for stage III non-small cell lung cancer: protocol for a systematic review and meta-analysis.<h4>Introduction</h4>Lung cancer continues to be a common form of cancer worldwide and a primary contributor to cancer-related fatalities. Non-small cell lung cancer (NSCLC) is the most prevalent form, making up 80% to 85% of newly identified malignant lung tumours, and remains a major concern for worldwide health. Surgical resection is the preferred treatment for localised NSCLC, but more than one-third of patients present with locally advanced, unresectable tumours. Concurrent radiation therapy and chemotherapy are believed to offer the potential for prolonged disease-free and overall survival to those patients. However, the results are inconsistent, and systematic meta-analysis is lacking to evaluate its treatment effect comprehensively. Therefore, we will conduct a meta-analysis to eva2024-01-01T00:00:00Z2024 Nov2026-07-16T18:55:43.858Z2025-04-04T00:32:58.228ZS-EPMC115520143951585810.1136/bmjopen-2024-090728