{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Thorpe P"],"funding":["Biotechnology and Biological Sciences Research Council"],"pagination":["1065"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11552303"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(1)"],"pubmed_abstract":["<h4>Background</h4>Compatibility between plant parasites and their hosts is genetically determined {Citation}both interacting organisms. For example, plants may carry resistance (R) genes or deploy chemical defences. Aphid saliva contains many proteins that are secreted into host tissues. Subsets of these proteins are predicted to act as effectors, either subverting or triggering host immunity. However, associating particular effectors with virulence or avirulence outcomes presents challenges due to the combinatorial complexity. Here we use defined aphid and host genetics to test for co-segregation of expressed aphid transcripts and proteins with virulent or avirulent phenotypes.<h4>Results</h4>We compared virulent and avirulent pea aphid parental genotypes, and their bulk segregant F1 pro"],"journal":["BMC genomics"],"pubmed_title":["Multi-omics approaches define novel aphid effector candidates associated with virulence and avirulence phenotypes."],"pmcid":["PMC11552303"],"funding_grant_id":["BB/N002660/1","BB/N002830/1"],"pubmed_authors":["Iqbal J","Turnbull C","Thorpe P","Lopez-Cobollo R","Douglas N","Bos J","Altmann S","Kanvil S","Simon JC","Carolan JC"],"additional_accession":[]},"is_claimable":false,"name":"Multi-omics approaches define novel aphid effector candidates associated with virulence and avirulence phenotypes.","description":"<h4>Background</h4>Compatibility between plant parasites and their hosts is genetically determined {Citation}both interacting organisms. For example, plants may carry resistance (R) genes or deploy chemical defences. Aphid saliva contains many proteins that are secreted into host tissues. Subsets of these proteins are predicted to act as effectors, either subverting or triggering host immunity. However, associating particular effectors with virulence or avirulence outcomes presents challenges due to the combinatorial complexity. Here we use defined aphid and host genetics to test for co-segregation of expressed aphid transcripts and proteins with virulent or avirulent phenotypes.<h4>Results</h4>We compared virulent and avirulent pea aphid parental genotypes, and their bulk segregant F1 pro","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2026-07-16T18:53:46.305Z","creation":"2025-04-04T00:32:45.451Z"},"accession":"S-EPMC11552303","cross_references":{"pubmed":["39528973"],"doi":["10.1186/s12864-024-10984-x"]}}