{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(1)"],"submitter":["Langenhorst J"],"funding":["Klinikum der Universität München"],"pubmed_abstract":["Targeted temperature management (TTM) with therapeutic hypothermia (TH) during aortic arch surgery requires valid estimations of core body temperature. The ear canal and epitympanic region might be an easy-to-assess, noninvasive site for the read-out of supra-aortic, cerebral temperature. This observational cohort study comparatively investigated in-ear temperature and different core body temperature (cBT) measurements during TTM/TH for moderate hypothermic circulatory arrest (mHCA) in aortic arch surgery. In total 24 patients (mean age of 56.8 ± 17.5 years; six females) were measured using infrared-thermography of the epitympanic region (BT<sub>tym</sub>), thermistor-based measurements at the esophagus (BT<sub>eso</sub>; gold standard), at the ear canal (BT<sub>ear</sub>), at the nasopharynx (BT<sub>nas</sub>), in the bladder (BT<sub>ves</sub>), and in the rectum (BT<sub>rec</sub>). The data analysis comprised absolute agreement (AA), bias, intraclass correlation coefficient (ICC), and limit of agreement (LoA). The results revealed high AAs of BT<sub>tym</sub>, BT<sub>ear</sub>, BT<sub>nas</sub> in reference to BT<sub>eso</sub> (biases 0.3-0.6 °C), with also excellent ICCs > 0.9. BT<sub>ves</sub> and BT<sub>rec</sub> showed lower AAs, higher biases of + 2.5 °C to 3.1 °C with moderate ICCs during mHCA. In the phases of rapid temperature changes, the biases and LoAs were higher throughout all BT measurements. Herein, BT<sub>tym</sub> performed best of all measurement sites. The study informs about the BT dynamics at different body sites during the mHCA procedure. It supports the approach of using minimally invasive in-ear techniques to estimate core body temperature in an intrahospital TTM/TH setting of mHCA."],"journal":["Scientific reports"],"pagination":["27607"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11554646"],"repository":["biostudies-literature"],"pubmed_title":["Agreement of in-ear temperature to core body temperature measures during invasive whole-body cooling for hypothermic circulatory arrest in aortic arch surgery."],"pmcid":["PMC11554646"],"pubmed_authors":["Bayer A","Prueckner S","Witte M","Scheiermann P","Feuerecker M","Scheiermann T","Langenhorst J","Pichlmaier M","Schniepp R","Benkert A","Peterss S"],"additional_accession":[]},"is_claimable":false,"name":"Agreement of in-ear temperature to core body temperature measures during invasive whole-body cooling for hypothermic circulatory arrest in aortic arch surgery.","description":"Targeted temperature management (TTM) with therapeutic hypothermia (TH) during aortic arch surgery requires valid estimations of core body temperature. The ear canal and epitympanic region might be an easy-to-assess, noninvasive site for the read-out of supra-aortic, cerebral temperature. This observational cohort study comparatively investigated in-ear temperature and different core body temperature (cBT) measurements during TTM/TH for moderate hypothermic circulatory arrest (mHCA) in aortic arch surgery. In total 24 patients (mean age of 56.8 ± 17.5 years; six females) were measured using infrared-thermography of the epitympanic region (BT<sub>tym</sub>), thermistor-based measurements at the esophagus (BT<sub>eso</sub>; gold standard), at the ear canal (BT<sub>ear</sub>), at the nasopharynx (BT<sub>nas</sub>), in the bladder (BT<sub>ves</sub>), and in the rectum (BT<sub>rec</sub>). The data analysis comprised absolute agreement (AA), bias, intraclass correlation coefficient (ICC), and limit of agreement (LoA). The results revealed high AAs of BT<sub>tym</sub>, BT<sub>ear</sub>, BT<sub>nas</sub> in reference to BT<sub>eso</sub> (biases 0.3-0.6 °C), with also excellent ICCs > 0.9. BT<sub>ves</sub> and BT<sub>rec</sub> showed lower AAs, higher biases of + 2.5 °C to 3.1 °C with moderate ICCs during mHCA. In the phases of rapid temperature changes, the biases and LoAs were higher throughout all BT measurements. Herein, BT<sub>tym</sub> performed best of all measurement sites. The study informs about the BT dynamics at different body sites during the mHCA procedure. It supports the approach of using minimally invasive in-ear techniques to estimate core body temperature in an intrahospital TTM/TH setting of mHCA.","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2025-07-03T03:06:00.834Z","creation":"2025-04-04T00:33:19.69Z"},"accession":"S-EPMC11554646","cross_references":{"pubmed":["39528634"],"doi":["10.1038/s41598-024-77237-5"]}}