{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["20(22)"],"submitter":["Cardaioli F"],"pubmed_abstract":["<h4>Background</h4>In patients undergoing transcatheter aortic valve implantation (TAVI), the presence of a low-flow, low-gradient (LFLG) status has been associated with higher mortality at short-term follow-up.<h4>Aims</h4>We aimed to evaluate long-term survival after TAVI in patients with classical (cLFLG) and paradoxical LFLG (pLFLG) aortic stenosis (AS) compared to high-gradient (HG)-AS.<h4>Methods</h4>Patients undergoing TAVI at our centre with a hypothetical minimum 5-year follow-up were divided into 3 groups: (1) HG-AS (mean gradient [MG] >40 mmHg), (2) cLFLG-AS (MG <40 mmHg, ejection fraction [EF] <50%), and (3) pLFLG-AS (MG <40 mmHg, EF ≥50%). The primary endpoint of the study was all-cause mortality. Propensity score-weighted survival analysis was performed to adjust for possible"],"journal":["EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology"],"pagination":["1380-1389"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11556328"],"repository":["biostudies-literature"],"pubmed_title":["Long-term survival after TAVI in low-flow, low-gradient aortic valve stenosis."],"pmcid":["PMC11556328"],"pubmed_authors":["Fovino LN","Arturi F","Fabris T","Bertolini A","Napodano M","Fraccaro C","Tarantini G","Continisio S","Cardaioli F","Lorenzoni G","Gregori D","Rodino G","Masiero G","Panza A"],"additional_accession":[]},"is_claimable":false,"name":"Long-term survival after TAVI in low-flow, low-gradient aortic valve stenosis.","description":"<h4>Background</h4>In patients undergoing transcatheter aortic valve implantation (TAVI), the presence of a low-flow, low-gradient (LFLG) status has been associated with higher mortality at short-term follow-up.<h4>Aims</h4>We aimed to evaluate long-term survival after TAVI in patients with classical (cLFLG) and paradoxical LFLG (pLFLG) aortic stenosis (AS) compared to high-gradient (HG)-AS.<h4>Methods</h4>Patients undergoing TAVI at our centre with a hypothetical minimum 5-year follow-up were divided into 3 groups: (1) HG-AS (mean gradient [MG] >40 mmHg), (2) cLFLG-AS (MG <40 mmHg, ejection fraction [EF] <50%), and (3) pLFLG-AS (MG <40 mmHg, EF ≥50%). The primary endpoint of the study was all-cause mortality. Propensity score-weighted survival analysis was performed to adjust for possible","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2026-06-09T05:39:44.158Z","creation":"2026-06-09T03:07:54.769Z"},"accession":"S-EPMC11556328","cross_references":{"pubmed":["39552481"],"doi":["10.4244/eij-d-24-00442","10.4244/EIJ-D-24-00442"]}}