biostudies-literatureUnknownChua ZXSingapore Heart FoundationSinghealth Medical Student Talent Development Award<h4>Purpose</h4>Secondhand smoke significantly increases the risk of cerebrovascular diseases, prompting recent public smoking bans. We aimed to ascertain the effects of smoke-free legislation on stroke incidence and mortality.<h4>Methods</h4>We systematically searched Medline, Embase, Cochrane Library, and Scopus up to August 13, 2023, for studies reporting changes in stroke incidence following partial or comprehensive smoking bans. A random-effects meta-analysis was conducted on hospital admissions and mortality for stroke, stratified based on comprehensiveness of the ban ((i) workplaces-only, (ii) workplaces and restaurants, (iii) workplaces, restaurants and bars). The effect of post-ban follow-up duration was assessed visually by a forest plot, while meta-regression was employed to evaEuropean stroke journal23969873241293566https://www.ebi.ac.uk/biostudies/studies/S-EPMC11556582biostudies-literatureImpact of smoke-free legislation on stroke risk: A systematic review and meta-analysis.PMC11556582Ho AFWYeh Lai Amanda COng JSPLim MJRTan BYQLim SYWAik JChua ZXLam TJRKumar SfalseImpact of smoke-free legislation on stroke risk: A systematic review and meta-analysis.<h4>Purpose</h4>Secondhand smoke significantly increases the risk of cerebrovascular diseases, prompting recent public smoking bans. We aimed to ascertain the effects of smoke-free legislation on stroke incidence and mortality.<h4>Methods</h4>We systematically searched Medline, Embase, Cochrane Library, and Scopus up to August 13, 2023, for studies reporting changes in stroke incidence following partial or comprehensive smoking bans. A random-effects meta-analysis was conducted on hospital admissions and mortality for stroke, stratified based on comprehensiveness of the ban ((i) workplaces-only, (ii) workplaces and restaurants, (iii) workplaces, restaurants and bars). The effect of post-ban follow-up duration was assessed visually by a forest plot, while meta-regression was employed to eva2024-01-01T00:00:00Z2024 Oct2025-04-18T12:48:18.644Z2025-04-06T22:09:43.047ZS-EPMC115565823947536110.1177/23969873241293566