{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Narciso A"],"funding":["Ministero dell'Istruzione, dell'Università e della Ricerca","Lazio Innova","Ministero dell’Istruzione, dell’Università e della Ricerca"],"pagination":["516"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11564247"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["108(1)"],"pubmed_abstract":["Cattle manure or its digestate, which often contains antibiotic residues, can be used as an organic fertilizer and copper (Cu) as a fungicide in agriculture. Consequently, both antibiotics and Cu are considered soil contaminants. In this work, microcosms were performed with soil amended with either manure or digestate with Cu and an antibiotic (sulfamethoxazole, SMX) co-presence and the planting of Lactuca sativa. After the addition of the organic amendments, a prompt increase in the microbial activity and at the same time of the sul1 and intI1 genes was observed, although ARGs generally decreased over time. In the amended and spiked microcosms, the microbial community was able to remove more than 99% of SMX in 36 days and the antibiotic did not bioaccumulate in the lettuce. Interestingly,"],"journal":["Applied microbiology and biotechnology"],"pubmed_title":["Effects of sulfamethoxazole and copper on the natural microbial community from a fertilized soil."],"pmcid":["PMC11564247"],"funding_grant_id":["CN00000022","CN_00000033","85-2017-15065"],"pubmed_authors":["Rolando L","Rauseo J","Alvarez-Alonso C","De Carolis C","Patrolecco L","Spataro F","Bustamante MA","Barra Caracciolo A","Grenni P","Garbini GL","Narciso A","Iannelli MA"],"additional_accession":[]},"is_claimable":false,"name":"Effects of sulfamethoxazole and copper on the natural microbial community from a fertilized soil.","description":"Cattle manure or its digestate, which often contains antibiotic residues, can be used as an organic fertilizer and copper (Cu) as a fungicide in agriculture. Consequently, both antibiotics and Cu are considered soil contaminants. In this work, microcosms were performed with soil amended with either manure or digestate with Cu and an antibiotic (sulfamethoxazole, SMX) co-presence and the planting of Lactuca sativa. After the addition of the organic amendments, a prompt increase in the microbial activity and at the same time of the sul1 and intI1 genes was observed, although ARGs generally decreased over time. In the amended and spiked microcosms, the microbial community was able to remove more than 99% of SMX in 36 days and the antibiotic did not bioaccumulate in the lettuce. Interestingly,","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2026-06-02T10:47:43.067Z","creation":"2025-04-04T00:22:00.945Z"},"accession":"S-EPMC11564247","cross_references":{"pubmed":["39540947"],"doi":["10.1007/s00253-024-13324-x"]}}