biostudies-literatureUnknown20Seppa AMJ<h4>Introduction</h4>Post-resuscitation care of cardiac arrest patients may be complicated by systemic inflammation elicited in response to whole-body ischaemia-reperfusion injury. We assessed the association between early WBC with one-year mortality in a large, unselected population of cardiac arrest patients.<h4>Methods</h4>We collected a retrospective multicentre cohort of ICU-treated CA patients from the Finnish national ICU registry. We used locally estimated scatterplot smoothing (LOESS) curve to assess the association between the most abnormal WBC of the first 24 h in the ICU with the likelihood of death within a year. Multivariable logistic regression analyses were performed to assess the independent association between WBC and one-year mortality. In nested cohort analysis, we testResuscitation plus100816https://www.ebi.ac.uk/biostudies/studies/S-EPMC11565414biostudies-literatureAssociation of white blood cell count with one-year mortality after cardiac arrest.PMC11565414Reinikainen MSeppa AMJPekkarinen PTRaj RVuopio HSkrifvars MBfalseAssociation of white blood cell count with one-year mortality after cardiac arrest.<h4>Introduction</h4>Post-resuscitation care of cardiac arrest patients may be complicated by systemic inflammation elicited in response to whole-body ischaemia-reperfusion injury. We assessed the association between early WBC with one-year mortality in a large, unselected population of cardiac arrest patients.<h4>Methods</h4>We collected a retrospective multicentre cohort of ICU-treated CA patients from the Finnish national ICU registry. We used locally estimated scatterplot smoothing (LOESS) curve to assess the association between the most abnormal WBC of the first 24 h in the ICU with the likelihood of death within a year. Multivariable logistic regression analyses were performed to assess the independent association between WBC and one-year mortality. In nested cohort analysis, we test2024-01-01T00:00:00Z2024 Dec2026-07-17T00:04:36.927Z2025-04-06T22:09:34.619ZS-EPMC115654143955449110.1016/j.resplu.2024.100816