biostudies-literaturePankratz VSNational Cancer InstituteNCI NIH HHS10732748241300653https://www.ebi.ac.uk/biostudies/studies/S-EPMC11565617biostudies-literatureUnknown31<h4>Background</h4>Colorectal cancer (CRC) incidence rates have been decreasing in the United States (US), but there is limited information about differences in these improvements among individuals from different racial and ethnic subgroups across different regions of the US.<h4>Methods</h4>Data from the National Program of Cancer Registries (NPCR) and the Surveillance, Epidemiology, and End Results (SEER) databases were used to examine trends in CRC incidence from 2001 to 2020 using a population-based retrospective cohort study. We obtained annual estimates of CRC incidence and used meta-regression analyses via weighted linear models to identify main effects and interactions that explained differences in CRC incidence trends among groups defined by race/ethnicity and US region while also Cancer control : journal of the Moffitt Cancer CenterRacial and Ethnic Disparities in Colorectal Cancer Incidence Trends Across Regions of the United States From 2001 to 2020 - A United States Cancer Statistics Analysis.PMC115656173P30CA118100R01 CA192967R01CA1929673P30CA118100-16S4P30 CA118100Pankratz VSAdsul PKosich MEnglish KEdwardson NMishra SIKanda DfalseRacial and Ethnic Disparities in Colorectal Cancer Incidence Trends Across Regions of the United States From 2001 to 2020 - A United States Cancer Statistics Analysis.<h4>Background</h4>Colorectal cancer (CRC) incidence rates have been decreasing in the United States (US), but there is limited information about differences in these improvements among individuals from different racial and ethnic subgroups across different regions of the US.<h4>Methods</h4>Data from the National Program of Cancer Registries (NPCR) and the Surveillance, Epidemiology, and End Results (SEER) databases were used to examine trends in CRC incidence from 2001 to 2020 using a population-based retrospective cohort study. We obtained annual estimates of CRC incidence and used meta-regression analyses via weighted linear models to identify main effects and interactions that explained differences in CRC incidence trends among groups defined by race/ethnicity and US region while also 2024-01-01T00:00:00Z2024 Jan-Dec2025-04-21T22:19:00.527Z2025-04-05T18:39:32.228ZS-EPMC115656173954398110.1177/10732748241300653