{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["6(4)"],"submitter":["Feller D"],"pubmed_abstract":["<h4>Objective</h4>To determine the association between patient-reported spinal morning stiffness and lumbar disc degeneration (LDD) and systemic inflammation, as measured by C-reactive protein (CRP), in older patients with non-specific back pain. The ultimate objective is to help shape a future definition of spinal osteoarthritis (OA).<h4>Design</h4>Baseline data from the Dutch \"Back Complaints in the Older Adults\" (BACE) study was used. The relationship between the severity and duration of patient-reported spinal morning stiffness, LDD (i.e., multilevel disc space narrowing and multilevel osteophytes), and CRP was assessed. Regression models adjusted for confounding variables were performed.<h4>Results</h4>Six hundred and seventy-five patients were included. The mean age was 66.52 years ("],"journal":["Osteoarthritis and cartilage open"],"pagination":["100535"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11566339"],"repository":["biostudies-literature"],"pubmed_title":["The association of spinal morning stiffness with lumbar disc degeneration and C-reactive protein: The back complaints in older adults (BACE) study."],"pmcid":["PMC11566339"],"pubmed_authors":["van den Berg R","Koes BW","Feller D","Bierma-Zeinstra SM","Oei EHG","Chiarotto A","Enthoven WTM"],"additional_accession":[]},"is_claimable":false,"name":"The association of spinal morning stiffness with lumbar disc degeneration and C-reactive protein: The back complaints in older adults (BACE) study.","description":"<h4>Objective</h4>To determine the association between patient-reported spinal morning stiffness and lumbar disc degeneration (LDD) and systemic inflammation, as measured by C-reactive protein (CRP), in older patients with non-specific back pain. The ultimate objective is to help shape a future definition of spinal osteoarthritis (OA).<h4>Design</h4>Baseline data from the Dutch \"Back Complaints in the Older Adults\" (BACE) study was used. The relationship between the severity and duration of patient-reported spinal morning stiffness, LDD (i.e., multilevel disc space narrowing and multilevel osteophytes), and CRP was assessed. Regression models adjusted for confounding variables were performed.<h4>Results</h4>Six hundred and seventy-five patients were included. The mean age was 66.52 years (","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2026-07-17T00:04:44.968Z","creation":"2025-04-06T22:09:55.798Z"},"accession":"S-EPMC11566339","cross_references":{"pubmed":["39554477"],"doi":["10.1016/j.ocarto.2024.100535"]}}