{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhu Y"],"funding":["China Conservation and Research Center for the Giant Panda Fund Project","Key Technologies of Wild Giant Panda Population and Habitat Protection in Giant Panda National Park"],"pagination":["515"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11566409"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["20(1)"],"pubmed_abstract":["<h4>Background</h4>In recent years, several giant pandas have suffered from testicular tumor, which has seriously affected giant panda health. However, the pathogenesis of testicular tumor in giant panda is still unclear. Studies have shown that miRNAs are involved in the occurrence and development of a variety of cancers. However, the effect of miRNAs on giant panda testicular tumor has been little studied. Therefore, this study explored the pathogenesis of giant panda testicular tumor through miRNA and mRNA sequencing, and screened out diagnostic markers of testicular tumor.<h4>Results</h4>Combined with phenotypic symptoms and pathological section results, three giant pandas were diagnosed with testicular tumor and divided into tumor group, and three other giant pandas were divided into "],"journal":["BMC veterinary research"],"pubmed_title":["Blood mir-331-3p is a potential diagnostic marker for giant panda (Ailuropoda melanoleuca) testicular tumor."],"pmcid":["PMC11566409"],"funding_grant_id":["CGF2024001","CCRCGP222316"],"pubmed_authors":["Wu K","Li C","Zhu Y","Li D","Wang C","Liu Q","Deng L","Yang B","Zhou X","Wei M","Huang Z","Qu Y","Chen X","Deng W"],"additional_accession":[]},"is_claimable":false,"name":"Blood mir-331-3p is a potential diagnostic marker for giant panda (Ailuropoda melanoleuca) testicular tumor.","description":"<h4>Background</h4>In recent years, several giant pandas have suffered from testicular tumor, which has seriously affected giant panda health. However, the pathogenesis of testicular tumor in giant panda is still unclear. Studies have shown that miRNAs are involved in the occurrence and development of a variety of cancers. However, the effect of miRNAs on giant panda testicular tumor has been little studied. Therefore, this study explored the pathogenesis of giant panda testicular tumor through miRNA and mRNA sequencing, and screened out diagnostic markers of testicular tumor.<h4>Results</h4>Combined with phenotypic symptoms and pathological section results, three giant pandas were diagnosed with testicular tumor and divided into tumor group, and three other giant pandas were divided into ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2026-04-08T18:38:11.662Z","creation":"2025-04-06T22:44:35.503Z"},"accession":"S-EPMC11566409","cross_references":{"pubmed":["39548579"],"doi":["10.1186/s12917-024-04326-y"]}}