biostudies-literatureSiewny LNHLBI NIH HHS5330-5338https://www.ebi.ac.uk/biostudies/studies/S-EPMC11568751biostudies-literatureUnknown8(20)<h4>Abstract</h4>To address acute vaso-occlusive episodes (VOEs), the leading cause of emergency department (ED) visits among individuals with sickle cell disease (SCD), we conducted the clinical study, ALIGN (An Individualized Pain Plan with Patient and Provider Access for Emergency Department care of SCD), across 8 sites. We hypothesized an improvement of 0.5 standard deviations in perceived quality of ED pain treatment of a VOE after implementing individualized pain plans (IPPs) accessible to both patients and providers. Patients with SCD were aged 18 to 45 years, owned a cell phone, and had an ED VOE visit within 90 days prior. Patients completed the perceived quality of care surveys at baseline and within 96 hours after an ED VOE visit. Providers completed surveys regarding comfort maBlood advancesImpact of an individualized pain plan to treat sickle cell disease vaso-occlusive episodes in the emergency department.PMC11568751U01 HL133990U01 HL134042U01 HL133964U01 HL133997U24 HL133948U01 HL134004U01 HL133994U01 HL133996U01 HL134007Melvin CLPreiss LTanabe PKing AHankins JSDavila NSiewny LMcCuskee SCarpenter CRLuo LTreadwell MColla JSGollan SSCox LMasese RVfalseImpact of an individualized pain plan to treat sickle cell disease vaso-occlusive episodes in the emergency department.<h4>Abstract</h4>To address acute vaso-occlusive episodes (VOEs), the leading cause of emergency department (ED) visits among individuals with sickle cell disease (SCD), we conducted the clinical study, ALIGN (An Individualized Pain Plan with Patient and Provider Access for Emergency Department care of SCD), across 8 sites. We hypothesized an improvement of 0.5 standard deviations in perceived quality of ED pain treatment of a VOE after implementing individualized pain plans (IPPs) accessible to both patients and providers. Patients with SCD were aged 18 to 45 years, owned a cell phone, and had an ED VOE visit within 90 days prior. Patients completed the perceived quality of care surveys at baseline and within 96 hours after an ED VOE visit. Providers completed surveys regarding comfort ma2024-01-01T00:00:00Z2024 Oct2026-06-02T03:36:33.853Z2025-04-04T12:01:32.638ZS-EPMC115687513881523010.1182/bloodadvances.2023012439