{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(1)"],"submitter":["Schulze-Zachau V"],"pubmed_abstract":["<h4>Introduction</h4>Thrombectomy complications remain poorly explored. This study aims to characterize periprocedural intracranial vessel perforation including the effect of thrombolysis on patient outcomes.<h4>Patients and methods</h4>In this multicenter retrospective cohort study, consecutive patients with vessel perforation during thrombectomy between January 2015 and April 2023 were included. Vessel perforation was defined as active extravasation on digital subtraction angiography. The primary outcome was modified Rankin Scale (mRS) at 90 days. Factors associated with the primary outcome were assessed using proportional odds models.<h4>Results</h4>459 patients with vessel perforation were included (mean age 72.5 ± 13.6 years, 59% female, 41% received thrombolysis). Mortality at 90 day"],"journal":["European stroke journal"],"pagination":["63-73"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11569593"],"repository":["biostudies-literature"],"pubmed_title":["Insights into vessel perforations during thrombectomy: Characteristics of a severe complication and the effect of thrombolysis."],"pmcid":["PMC11569593"],"pubmed_authors":["Starke RM","Dobrocky T","Schulze-Zachau V","Regenhardt RW","van den Bergh F","De Raedt S","Rautio R","Schmeel C","Manning N","Commodaro C","Taylor A","Spiotta AM","Fischer U","Berlis A","Ojeda DJ","Pereira VM","Abdelsalam A","Sauer M","Weiss D","Tsogkas I","Khalife J","Bester M","Rommers N","Abu Qdais A","Schwab R","Rodrigo-Gisbert M","Kaschner M","Levitt MR","McQuinn A","Kirschke JS","Michel P","Althaus K","Lopez-Frias A","Limbucci N","Bellante F","Krug N","Jesser J","Raub SL","Serrallach BL","Maslias E","Mutke M","Dmytriw AA","Machi P","Cuberi A","Psychogios MN","Rodriguez-Ares T","Hofmeister J","Katan M","Cervo A","Moreu M","Karwacki GM","Cancelliere NM","Flottmann F","Ntoulias N","Dorn F","Samaniego EA","Rollo C","Kreiser K","Al Kasab S","Edhayan G","Patel AB","Perez-Garcia C","Renieri L","Rusche T","Pauli Y","Requena M","Nolte CH","Riegler C","Nawabi J","Maurer CJ","Kan PT","Thomas AJ","Fragata I","Pileggi M","Dusart A","Kaiser DP","Mohlenbruch M","Brehm A","Shaikh HA","Saliou G","Schwarting J"],"additional_accession":[]},"is_claimable":false,"name":"Insights into vessel perforations during thrombectomy: Characteristics of a severe complication and the effect of thrombolysis.","description":"<h4>Introduction</h4>Thrombectomy complications remain poorly explored. This study aims to characterize periprocedural intracranial vessel perforation including the effect of thrombolysis on patient outcomes.<h4>Patients and methods</h4>In this multicenter retrospective cohort study, consecutive patients with vessel perforation during thrombectomy between January 2015 and April 2023 were included. Vessel perforation was defined as active extravasation on digital subtraction angiography. The primary outcome was modified Rankin Scale (mRS) at 90 days. Factors associated with the primary outcome were assessed using proportional odds models.<h4>Results</h4>459 patients with vessel perforation were included (mean age 72.5 ± 13.6 years, 59% female, 41% received thrombolysis). Mortality at 90 day","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Mar","modification":"2026-07-16T23:49:01.397Z","creation":"2025-04-06T01:56:28.225Z"},"accession":"S-EPMC11569593","cross_references":{"pubmed":["39171391"],"doi":["10.1177/23969873241272542"]}}