biostudies-literatureUnknown16Flanigan JL<h4>Background</h4>Parkinson's disease psychosis (PDPsy) is associated with increased nursing home placement and mortality and is closely linked with cognitive dysfunction.<h4>Objective</h4>Assess the clinical and cognitive features associated with PDPsy in patients without dementia.<h4>Methods</h4>We prospectively recruited people with Parkinson's disease (PwP) without dementia for a 3-year, longitudinal study at an outpatient movement disorders clinic. Participants completed annual visits involving assessment of motor and non-motor symptoms including neuropsychological testing. PDPsy was defined as the recurring presence of visual illusions, sense of presence, hallucinations, or delusions for at least 1 month. Using generalized estimating equations, we conducted two sets of analyses to sFrontiers in aging neuroscience1463426https://www.ebi.ac.uk/biostudies/studies/S-EPMC11579864biostudies-literatureClinical and cognitive features associated with psychosis in Parkinson's disease: a longitudinal study.PMC11579864Sperling SAShah BBPatrie JTWyman-Chick KADalrymple WAFlanigan JLHarrison MBBarrett MJfalseClinical and cognitive features associated with psychosis in Parkinson's disease: a longitudinal study.<h4>Background</h4>Parkinson's disease psychosis (PDPsy) is associated with increased nursing home placement and mortality and is closely linked with cognitive dysfunction.<h4>Objective</h4>Assess the clinical and cognitive features associated with PDPsy in patients without dementia.<h4>Methods</h4>We prospectively recruited people with Parkinson's disease (PwP) without dementia for a 3-year, longitudinal study at an outpatient movement disorders clinic. Participants completed annual visits involving assessment of motor and non-motor symptoms including neuropsychological testing. PDPsy was defined as the recurring presence of visual illusions, sense of presence, hallucinations, or delusions for at least 1 month. Using generalized estimating equations, we conducted two sets of analyses to s2024-01-01T00:00:00Z20242025-04-04T13:41:44.935Z2025-04-04T13:41:44.935ZS-EPMC115798643957448810.3389/fnagi.2024.1463426