biostudies-literatureUnknownRomoli MBando Ricerca Corrente<h4>Introduction</h4>Data on safety and efficacy of endovascular thrombectomy (EVT) for acute ischemic stroke in older patients are limited and controversial, and people aged 80 or older were under-represented in randomized trials. Our aim was to assess EVT effect for ischemic stroke patients aged ⩾80 at a nationwide level.<h4>Patients and methods</h4>The cohort included stroke patients undergoing EVT from the Italian Registry of Endovascular Treatment in Acute Stroke (IRETAS). Patients were a priori divided into younger and older groups (<80 vs ⩾80). Primary outcome was good functional outcome (modified Rankin scale, mRS, 0-2 at 90 days). Secondary outcomes were symptomatic intracranial hemorrhage (sICH), successful reperfusion, EVT abortion. Propensity score matching (PSM) was performed European stroke journal23969873241299335https://www.ebi.ac.uk/biostudies/studies/S-EPMC11579997biostudies-literatureStroke thrombectomy in the elderly: A propensity score matched study on a nationwide real-world registry.PMC11579997La Spina PRusso MBracco SGiossi APezzini AGiannini NPlebani MCerrato PFerrandi DNaldi ADall'Ora ECastellano DTassi RSaia VLoizzo NDNappini SCavasin NFainardi EToni DCritelli ACirillo LBurdi NMannino MRomano DMangiafico SBoero GMigliaccio LAmista PBesana MBigliardi GGallesio ILimbucci NNencini PCasalena ANicolini ERizzo AZimatore SBenzi Markushi TTassinari TCastellan LPracucci GVinci SLBergui MPuglielli ESallustio FOrlandi BSaletti AInvernizzi PFilauri PPaladini AIvaldi DPetruzzellis MPavia MCasetta IZini AVallone SLazzarotti GAFilizzolo MAzzini CBiraschi FRomoli MFrauenfelder GDiomedi MRuggiero MMenozzi RComai AForlivesi SDa Ros VCappellari MfalseStroke thrombectomy in the elderly: A propensity score matched study on a nationwide real-world registry.<h4>Introduction</h4>Data on safety and efficacy of endovascular thrombectomy (EVT) for acute ischemic stroke in older patients are limited and controversial, and people aged 80 or older were under-represented in randomized trials. Our aim was to assess EVT effect for ischemic stroke patients aged ⩾80 at a nationwide level.<h4>Patients and methods</h4>The cohort included stroke patients undergoing EVT from the Italian Registry of Endovascular Treatment in Acute Stroke (IRETAS). Patients were a priori divided into younger and older groups (<80 vs ⩾80). Primary outcome was good functional outcome (modified Rankin scale, mRS, 0-2 at 90 days). Secondary outcomes were symptomatic intracranial hemorrhage (sICH), successful reperfusion, EVT abortion. Propensity score matching (PSM) was performed 2024-01-01T00:00:00Z2024 Nov2025-04-04T13:41:01.652Z2025-04-04T13:41:01.652ZS-EPMC115799973956503510.1177/23969873241299335