{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hohl CM"],"funding":["Public Health Agency of Canada/COVID-19 Immunity Task Force","Fonds de recherche du Québec – Santé","Ontario Ministry of Colleges and Universities","Saskatchewan Health Research Foundation","BioTalent Canada","Genome British Columbia","Fondation du CHU de Québec","BC Academic Health Science Network","Canadian Institutes of Health Research"],"pagination":["e083280"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11580276"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(11)"],"pubmed_abstract":["<h4>Objective</h4>The objective is to externally validate and assess the opportunity to update the Canadian COVID-19 Mortality Score (CCMS) to predict in-hospital mortality among consecutive non-palliative COVID-19 patients infected with Omicron subvariants at a time when vaccinations were widespread.<h4>Design</h4>This observational study validated the CCMS in an external cohort at a time when Omicron variants were dominant. We assessed the potential to update the rule and improve its performance by recalibrating and adding vaccination status in a subset of patients from provinces with access to vaccination data and created the adjusted CCMS (CCMS<sup>adj</sup>). We followed discharged patients for 30 days after their index emergency department visit or for their entire hospital stay if a"],"journal":["BMJ open"],"pubmed_title":["Accuracy of the Canadian COVID-19 Mortality Score (CCMS) to predict in-hospital mortality among vaccinated and unvaccinated patients infected with Omicron: a cohort study."],"pmcid":["PMC11580276"],"funding_grant_id":["N/A","2122-HQ-000054","447679","5357","4007","C-655-2129","VAC007","COV024"],"pubmed_authors":["Clark G","McRae A","Grant L","Dahn T","Stachura M","Chandra K","Khangura J","Daoust R","Rowe B","Mohindra R","Davis P","CCEDRRN investigators for the Network of Canadian Emergency Researchers and the Canadian Critical Care Trials Group","Wiemer H","Haward J","Taylor J","Turner J","Yeom DS","Brar B","Martin I","Archambault PM","Fok P","Welsford M","Landes M","Cheng I","Ohle R","Wormsbecker S","Ting D","Yan J","Arsenault K","Perry J","Robert S","Morrison LJ","Hohl CM","Campbell S","Mercier E","Graham L","VandenBerg S","Jelic T","Scheuermeyer F","Purssell E","Brooks SC","Rosychuk R","Lin K"],"additional_accession":[]},"is_claimable":false,"name":"Accuracy of the Canadian COVID-19 Mortality Score (CCMS) to predict in-hospital mortality among vaccinated and unvaccinated patients infected with Omicron: a cohort study.","description":"<h4>Objective</h4>The objective is to externally validate and assess the opportunity to update the Canadian COVID-19 Mortality Score (CCMS) to predict in-hospital mortality among consecutive non-palliative COVID-19 patients infected with Omicron subvariants at a time when vaccinations were widespread.<h4>Design</h4>This observational study validated the CCMS in an external cohort at a time when Omicron variants were dominant. We assessed the potential to update the rule and improve its performance by recalibrating and adding vaccination status in a subset of patients from provinces with access to vaccination data and created the adjusted CCMS (CCMS<sup>adj</sup>). We followed discharged patients for 30 days after their index emergency department visit or for their entire hospital stay if a","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2025-04-04T13:41:12.9Z","creation":"2025-04-04T13:41:12.9Z"},"accession":"S-EPMC11580276","cross_references":{"pubmed":["39566942"],"doi":["10.1136/bmjopen-2023-083280"]}}