{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Binotti WW"],"funding":["Tufts Medical Center","NEI NIH HHS","Research to Prevent Blindness","Massachusetts Lions Eye Research Fund Inc"],"pagination":["86-93"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11583202"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["22"],"pubmed_abstract":["<h4>Purpose</h4>Describe the utility of anterior segment optical coherence tomography angiography (AS-OCTA) to assess ocular surface lesions.<h4>Methods</h4>Retrospective, case-control study of 10 eyes of 9 patients with malignant lesions and 23 eyes of 22 patients with benign lesions. Lesions included 13 epithelial, 10 pigmented and 10 lymphoid lesions. Graders performed an average of 3 depth and diameter measurements of peri-lesional vessels entering each lesion on AS-OCTA. Statistical models to assess differences between groups accounted for bilateral eye inclusion and lesion thickness (on AS-OCT). Receiver operating characteristic (ROC) curve and area under the curve (AUC) were performed for each parameter.<h4>Results</h4>In the benign and malignant groups, age was 49.5 ± 22.4 and 64.3"],"journal":["The ocular surface"],"pubmed_title":["Anterior segment optical coherence tomography angiography in the assessment of ocular surface lesions."],"pmcid":["PMC11583202"],"funding_grant_id":["R01 EY029602"],"pubmed_authors":["Hamrah P","Duker JS","Binotti WW","Nose RM","Wu HK","Mills H"],"additional_accession":[]},"is_claimable":false,"name":"Anterior segment optical coherence tomography angiography in the assessment of ocular surface lesions.","description":"<h4>Purpose</h4>Describe the utility of anterior segment optical coherence tomography angiography (AS-OCTA) to assess ocular surface lesions.<h4>Methods</h4>Retrospective, case-control study of 10 eyes of 9 patients with malignant lesions and 23 eyes of 22 patients with benign lesions. Lesions included 13 epithelial, 10 pigmented and 10 lymphoid lesions. Graders performed an average of 3 depth and diameter measurements of peri-lesional vessels entering each lesion on AS-OCTA. Statistical models to assess differences between groups accounted for bilateral eye inclusion and lesion thickness (on AS-OCT). Receiver operating characteristic (ROC) curve and area under the curve (AUC) were performed for each parameter.<h4>Results</h4>In the benign and malignant groups, age was 49.5 ± 22.4 and 64.3","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Oct","modification":"2025-04-04T13:41:46.722Z","creation":"2025-04-04T13:41:46.722Z"},"accession":"S-EPMC11583202","cross_references":{"pubmed":["34333154"],"doi":["10.1016/j.jtos.2021.07.009"]}}