biostudies-literatureBinotti WWTufts Medical CenterNEI NIH HHSResearch to Prevent BlindnessMassachusetts Lions Eye Research Fund Inc86-93https://www.ebi.ac.uk/biostudies/studies/S-EPMC11583202biostudies-literatureUnknown22<h4>Purpose</h4>Describe the utility of anterior segment optical coherence tomography angiography (AS-OCTA) to assess ocular surface lesions.<h4>Methods</h4>Retrospective, case-control study of 10 eyes of 9 patients with malignant lesions and 23 eyes of 22 patients with benign lesions. Lesions included 13 epithelial, 10 pigmented and 10 lymphoid lesions. Graders performed an average of 3 depth and diameter measurements of peri-lesional vessels entering each lesion on AS-OCTA. Statistical models to assess differences between groups accounted for bilateral eye inclusion and lesion thickness (on AS-OCT). Receiver operating characteristic (ROC) curve and area under the curve (AUC) were performed for each parameter.<h4>Results</h4>In the benign and malignant groups, age was 49.5 ± 22.4 and 64.3The ocular surfaceAnterior segment optical coherence tomography angiography in the assessment of ocular surface lesions.PMC11583202R01 EY029602Hamrah PDuker JSBinotti WWNose RMWu HKMills HfalseAnterior segment optical coherence tomography angiography in the assessment of ocular surface lesions.<h4>Purpose</h4>Describe the utility of anterior segment optical coherence tomography angiography (AS-OCTA) to assess ocular surface lesions.<h4>Methods</h4>Retrospective, case-control study of 10 eyes of 9 patients with malignant lesions and 23 eyes of 22 patients with benign lesions. Lesions included 13 epithelial, 10 pigmented and 10 lymphoid lesions. Graders performed an average of 3 depth and diameter measurements of peri-lesional vessels entering each lesion on AS-OCTA. Statistical models to assess differences between groups accounted for bilateral eye inclusion and lesion thickness (on AS-OCT). Receiver operating characteristic (ROC) curve and area under the curve (AUC) were performed for each parameter.<h4>Results</h4>In the benign and malignant groups, age was 49.5 ± 22.4 and 64.32021-01-01T00:00:00Z2021 Oct2025-04-04T13:41:46.722Z2025-04-04T13:41:46.722ZS-EPMC115832023433315410.1016/j.jtos.2021.07.009