{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["22(11)"],"submitter":["Atalay Ekiner S"],"funding":["Ministry of Science and Higher Education (Poland)"],"pubmed_abstract":["Lipid extracts from the microalgae <i>Nannochloropsis oceanica</i> and <i>Chlorococcum amblystomatis</i> have great potential to prevent ultraviolet A (UVA)-induced metabolic disorders. Therefore, the aim of this study has been to analyze their cytoprotective effect, focused on maintaining intracellular redox balance and inflammation in UVA-irradiated skin fibroblasts, at the proteome level. The above lipid extracts reversed the suppression of the antioxidant response caused by UVA radiation, which was more visible in the case of <i>C. amblystomatis</i>. Modulations of interactions between heme oxygenase-1 and matrix metalloproteinase 1/Parkinson's disease protein 7/transcript1-α/β, as well as thioredoxin and migration inhibitory factor/Parkinson's disease protein 7/calnexin/ATPase p97, cr"],"journal":["Marine drugs"],"pagination":["509"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11595653"],"repository":["biostudies-literature"],"pubmed_title":["Comparison of Microalgae <i>Nannochloropsis oceanica</i> and <i>Chlorococcum amblystomatis</i> Lipid Extracts Effects on UVA-Induced Changes in Human Skin Fibroblasts Proteome."],"pmcid":["PMC11595653"],"pubmed_authors":["Domingues P","Skrzydlewska E","Atalay Ekiner S","Gegotek A","Domingues MR"],"additional_accession":[]},"is_claimable":false,"name":"Comparison of Microalgae <i>Nannochloropsis oceanica</i> and <i>Chlorococcum amblystomatis</i> Lipid Extracts Effects on UVA-Induced Changes in Human Skin Fibroblasts Proteome.","description":"Lipid extracts from the microalgae <i>Nannochloropsis oceanica</i> and <i>Chlorococcum amblystomatis</i> have great potential to prevent ultraviolet A (UVA)-induced metabolic disorders. Therefore, the aim of this study has been to analyze their cytoprotective effect, focused on maintaining intracellular redox balance and inflammation in UVA-irradiated skin fibroblasts, at the proteome level. The above lipid extracts reversed the suppression of the antioxidant response caused by UVA radiation, which was more visible in the case of <i>C. amblystomatis</i>. Modulations of interactions between heme oxygenase-1 and matrix metalloproteinase 1/Parkinson's disease protein 7/transcript1-α/β, as well as thioredoxin and migration inhibitory factor/Parkinson's disease protein 7/calnexin/ATPase p97, cr","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2026-05-27T03:17:22.414Z","creation":"2025-04-04T00:46:41.949Z"},"accession":"S-EPMC11595653","cross_references":{"pubmed":["39590789"],"doi":["10.3390/md22110509"]}}