{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["23(2)"],"submitter":["Efthymiadis A"],"pubmed_abstract":["<h4>Objectives</h4>Impaired awareness of hyperglycaemia (IAH) affects approximately 20-40% of people living with type 1 diabetes (T1D), predisposing them to severe hypoglycaemia. This systematic review evaluated the efficacy of closed-loop automated insulin delivery systems (CL-AID) in restoring IAH compared with standard diabetes care, including other diabetes technologies.<h4>Methods</h4>Six electronic databases were searched for published and unpublished observational and randomised-control studies (RCTs) from inception to 29th of May 2024. The results of observational studies and RCTs were meta-analysed separately to calculate the effect of CL-AID on IAH in people living with T1D. Quality assessment of studies was performed using the Joanna-Briggs appraisal tool for cohort studies and "],"journal":["Journal of diabetes and metabolic disorders"],"pagination":["2251-2261"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11599659"],"repository":["biostudies-literature"],"pubmed_title":["The impact of closed-loop automated insulin delivery systems on hypoglycaemia awareness in people living with type 1 diabetes: A systematic review and meta-analysis."],"pmcid":["PMC11599659"],"pubmed_authors":["Spinos D","Efthymiadis A","Liu L","Bourlaki M","Tsikopoulos K","Bastounis A"],"additional_accession":[]},"is_claimable":false,"name":"The impact of closed-loop automated insulin delivery systems on hypoglycaemia awareness in people living with type 1 diabetes: A systematic review and meta-analysis.","description":"<h4>Objectives</h4>Impaired awareness of hyperglycaemia (IAH) affects approximately 20-40% of people living with type 1 diabetes (T1D), predisposing them to severe hypoglycaemia. This systematic review evaluated the efficacy of closed-loop automated insulin delivery systems (CL-AID) in restoring IAH compared with standard diabetes care, including other diabetes technologies.<h4>Methods</h4>Six electronic databases were searched for published and unpublished observational and randomised-control studies (RCTs) from inception to 29th of May 2024. The results of observational studies and RCTs were meta-analysed separately to calculate the effect of CL-AID on IAH in people living with T1D. Quality assessment of studies was performed using the Joanna-Briggs appraisal tool for cohort studies and ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2026-05-29T20:11:20.529Z","creation":"2026-04-08T05:59:41.531Z"},"accession":"S-EPMC11599659","cross_references":{"pubmed":["39610490"],"doi":["10.1007/s40200-024-01492-6"]}}