{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Liu H"],"funding":["Taishan Scholar Foundation of Shandong Province ","Natural Science Foundation of Shandong Province","National Natural Science Foundation of China","Natural Science Foundation of Shandong"],"pagination":["e2409778"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11600196"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(44)"],"pubmed_abstract":["Endometriosis is a prevalent gynecological condition characterized by chronic pelvic pain, dysmenorrhea, and infertility, affecting ≈176 million women of reproductive age worldwide. Current treatments, including pharmacological and surgical interventions, are often associated with significant side effects and high recurrence rates. Consequently, there is an urgent need for innovative and safer therapeutic approaches. In this study, an injectable magnetic hydrogel nanosystem is developed designed for the dual-purpose magnetothermal and anti-inflammatory treatment of endometriosis. This hydrogel incorporates Fe<sub>3</sub>O<sub>4</sub> nanoparticles alongside an anti-inflammatory peptide. Upon magnetic activation, the Fe<sub>3</sub>O<sub>4</sub> nanoparticles induce a localized hyperthermic "],"journal":["Advanced science (Weinheim, Baden-Wurttemberg, Germany)"],"pubmed_title":["Injectable Magnetic Hydrogel Incorporated with Anti-Inflammatory Peptide for Efficient Magnetothermal Treatment of Endometriosis."],"pmcid":["PMC11600196"],"funding_grant_id":["tsqn202408248","ZR2023MH326","81801476"],"pubmed_authors":["Liu H","Li Y","Ren K","Wan J","Zhang L","Sun X","Wang Z","Dai X","Li N"],"additional_accession":[]},"is_claimable":false,"name":"Injectable Magnetic Hydrogel Incorporated with Anti-Inflammatory Peptide for Efficient Magnetothermal Treatment of Endometriosis.","description":"Endometriosis is a prevalent gynecological condition characterized by chronic pelvic pain, dysmenorrhea, and infertility, affecting ≈176 million women of reproductive age worldwide. Current treatments, including pharmacological and surgical interventions, are often associated with significant side effects and high recurrence rates. Consequently, there is an urgent need for innovative and safer therapeutic approaches. In this study, an injectable magnetic hydrogel nanosystem is developed designed for the dual-purpose magnetothermal and anti-inflammatory treatment of endometriosis. This hydrogel incorporates Fe<sub>3</sub>O<sub>4</sub> nanoparticles alongside an anti-inflammatory peptide. Upon magnetic activation, the Fe<sub>3</sub>O<sub>4</sub> nanoparticles induce a localized hyperthermic ","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2025-04-22T14:21:58.026Z","creation":"2025-04-06T01:02:53.425Z"},"accession":"S-EPMC11600196","cross_references":{"pubmed":["39373358"],"doi":["10.1002/advs.202409778"]}}