biostudies-literatureUnknown24(1)Zhao T<h4>Background</h4>Cancer survivors face many challenges in long-term health management, including malnutrition, systemic inflammation, and sleep issues, which significantly affect their survival and quality of life.<h4>Methods</h4>A prospective cohort study was derived from the National Health and Nutrition Examination Survey from 2005-2018 harboring 1,908 cancer survivors (weighted population, 11,453,293), of whom 688 deaths (220 from cancer mortality, 468 from non-cancer mortality). The Advanced Lung Cancer Inflammation Index (ALI) was used as a measure of nutritional status and systemic inflammation in cancer patients. Weighted multivariable Cox proportional hazards regression models were utilized to explore the independent and combined effects of ALI and sleep quality on mortality outBMC cancer1456https://www.ebi.ac.uk/biostudies/studies/S-EPMC11600600biostudies-literatureCombined effects of nutrition, inflammatory status, and sleep quality on mortality in cancer survivors.PMC11600600Liu LZhang XJiang XZhao TNi SYu JJiao YDai JLiang QDu MZhao HfalseCombined effects of nutrition, inflammatory status, and sleep quality on mortality in cancer survivors.<h4>Background</h4>Cancer survivors face many challenges in long-term health management, including malnutrition, systemic inflammation, and sleep issues, which significantly affect their survival and quality of life.<h4>Methods</h4>A prospective cohort study was derived from the National Health and Nutrition Examination Survey from 2005-2018 harboring 1,908 cancer survivors (weighted population, 11,453,293), of whom 688 deaths (220 from cancer mortality, 468 from non-cancer mortality). The Advanced Lung Cancer Inflammation Index (ALI) was used as a measure of nutritional status and systemic inflammation in cancer patients. Weighted multivariable Cox proportional hazards regression models were utilized to explore the independent and combined effects of ALI and sleep quality on mortality out2024-01-01T00:00:00Z2024 Nov2025-04-18T13:06:37.454Z2025-04-04T02:43:40.962ZS-EPMC116006003959297710.1186/s12885-024-13181-x