{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Conoan Nieves NE"],"funding":["NIGMS NIH HHS"],"pubmed_abstract":["The Class II NAD<sup>+</sup> riboswitch is a bacterial RNA that binds ligands containing nicotinamide. Herein, we report a fluorescence and biolayer interferometry study of riboswitch interactions with β-NMN. The results reveal a shift in the prevalence of a pseudoknot structure in the presence of ligand and Mg<sup>2+</sup>."],"journal":["bioRxiv : the preprint server for biology"],"pagination":["2024.11.10.622884"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11601409"],"repository":["biostudies-literature"],"pubmed_title":["Ligand binding characteristics of an NAD+ riboswitch revealed by FRET and biolayer interferometry."],"pmcid":["PMC11601409"],"funding_grant_id":["R35 GM147229"],"pubmed_authors":["Conoan Nieves NE","Widom JR"],"additional_accession":[]},"is_claimable":false,"name":"Ligand binding characteristics of an NAD+ riboswitch revealed by FRET and biolayer interferometry.","description":"The Class II NAD<sup>+</sup> riboswitch is a bacterial RNA that binds ligands containing nicotinamide. Herein, we report a fluorescence and biolayer interferometry study of riboswitch interactions with β-NMN. The results reveal a shift in the prevalence of a pseudoknot structure in the presence of ligand and Mg<sup>2+</sup>.","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2026-04-07T14:53:23.667Z","creation":"2025-04-03T23:56:17.119Z"},"accession":"S-EPMC11601409","cross_references":{"pubmed":["39605703"],"doi":["10.1101/2024.11.10.622884"]}}