{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang GL"],"funding":["NIAID NIH HHS"],"pagination":["W180-3"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC1160239"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["33(Web Server issue)"],"pubmed_abstract":["PRED(BALB/c) is a computational system that predicts peptides binding to the major histocompatibility complex-2 (H2(d)) of the BALB/c mouse, an important laboratory model organism. The predictions include the complete set of H2(d) class I (H2-K(d), H2-L(d) and H2-D(d)) and class II (I-E(d) and I-A(d)) molecules. The prediction system utilizes quantitative matrices, which were rigorously validated using experimentally determined binders and non-binders and also by in vivo studies using viral proteins. The prediction performance of PRED(BALB/c) is of very high accuracy. To our knowledge, this is the first online server for the prediction of peptides binding to a complete set of major histocompatibility complex molecules in a model organism (H2(d) haplotype). PRED(BALB/c) is available at http://antigen.i2r.a-star.edu.sg/predBalbc/."],"journal":["Nucleic acids research"],"pubmed_title":["PREDBALB/c: a system for the prediction of peptide binding to H2d molecules, a haplotype of the BALB/c mouse."],"pmcid":["PMC1160239"],"funding_grant_id":["U19 AI056541","5 U19 AI56541"],"pubmed_authors":["Srinivasan KN","August JT","Zhang GL","Brusic V","Veeramani A"],"additional_accession":[]},"is_claimable":false,"name":"PREDBALB/c: a system for the prediction of peptide binding to H2d molecules, a haplotype of the BALB/c mouse.","description":"PRED(BALB/c) is a computational system that predicts peptides binding to the major histocompatibility complex-2 (H2(d)) of the BALB/c mouse, an important laboratory model organism. The predictions include the complete set of H2(d) class I (H2-K(d), H2-L(d) and H2-D(d)) and class II (I-E(d) and I-A(d)) molecules. The prediction system utilizes quantitative matrices, which were rigorously validated using experimentally determined binders and non-binders and also by in vivo studies using viral proteins. The prediction performance of PRED(BALB/c) is of very high accuracy. To our knowledge, this is the first online server for the prediction of peptides binding to a complete set of major histocompatibility complex molecules in a model organism (H2(d) haplotype). PRED(BALB/c) is available at http://antigen.i2r.a-star.edu.sg/predBalbc/.","dates":{"release":"2005-01-01T00:00:00Z","publication":"2005 Jul","modification":"2025-06-01T00:32:35.806Z","creation":"2025-06-01T00:32:35.806Z"},"accession":"S-EPMC1160239","cross_references":{"pubmed":["15980450"],"doi":["10.1093/nar/gki479"]}}