biostudies-literatureLiang JNational Natural Science Foundation of China102https://www.ebi.ac.uk/biostudies/studies/S-EPMC11603884biostudies-literatureUnknown22(1)<h4>Objective</h4>This study aims to establish EQ-5D-Y-3L population norms in Jiangsu, China by conducting a large-scale cross-sectional survey.<h4>Methods</h4>Children and adolescents aged 9-17 from three cities of Jiangsu Province were selected by multistage stratified random sampling to complete the EQ-5D-Y-3L instrument independently. Population norms for Jiangsu, China were determined by calculating statistics based on age and gender. Logistic and Tobit regression models were employed to explain the relationship between HRQoL and factors such as sociodemographic characteristics/recent acute symptoms (experienced fever/cough/sore throat/diarrhea in the past two weeks).<h4>Results</h4>Three cities yielded 37,574 valid samples (a sample validity rate of 95.4%). The EQ-5D-Y-3L utility valHealth and quality of life outcomesEQ‑5D‑Y-3L population norms for children and adolescents in Jiangsu, China.PMC1160388472074122Yang JLiu LDong HWu QLiang JXu XYou HfalseEQ‑5D‑Y-3L population norms for children and adolescents in Jiangsu, China.<h4>Objective</h4>This study aims to establish EQ-5D-Y-3L population norms in Jiangsu, China by conducting a large-scale cross-sectional survey.<h4>Methods</h4>Children and adolescents aged 9-17 from three cities of Jiangsu Province were selected by multistage stratified random sampling to complete the EQ-5D-Y-3L instrument independently. Population norms for Jiangsu, China were determined by calculating statistics based on age and gender. Logistic and Tobit regression models were employed to explain the relationship between HRQoL and factors such as sociodemographic characteristics/recent acute symptoms (experienced fever/cough/sore throat/diarrhea in the past two weeks).<h4>Results</h4>Three cities yielded 37,574 valid samples (a sample validity rate of 95.4%). The EQ-5D-Y-3L utility val2024-01-01T00:00:00Z2024 Nov2025-04-22T20:37:28.269Z2025-04-06T03:16:44.437ZS-EPMC116038843960984510.1186/s12955-024-02322-2