{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["31(6)"],"submitter":["Lembo M"],"funding":["Università degli Studi di Napoli Federico II"],"pubmed_abstract":["<h4>Introduction</h4>Delay in arterial hypertension (AH) diagnosis and late therapy initiation may affect progression towards hypertensive-mediated organ damage (HMOD) and blood pressure (BP) control.<h4>Aim</h4>We aimed to assess the impact of time-to-therapy on BP control and HMOD in patients receiving AH diagnosis.<h4>Methods</h4>We analysed data from the Campania Salute Network, a prospective registry of hypertensive patients (NCT02211365). At baseline visit, time-to-therapy was defined as the interval between the first occurrence of BP values exceeding guidelines-directed thresholds and therapy initiation; HMOD included left ventricular hypertrophy (LVH), carotid plaque, or chronic kidney disease. Optimal BP control was considered for average values < 140/90 mmHg. Low-risk profile was"],"journal":["High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension"],"pagination":["639-648"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11604795"],"repository":["biostudies-literature"],"pubmed_title":["Prolonged Time-to-antihypertensive Therapy Worsens Organ Damage and Blood Pressure Control in Arterial Hypertension."],"pmcid":["PMC11604795"],"pubmed_authors":["Morisco C","Pacella D","Piccolo R","Mancusi C","Lembo M","Canciello G","Trimarco B","Bardi L","Manzi MV","Losi MA","Carnevale D","Esposito G","Izzo R","Giugliano G","Bossone E"],"additional_accession":[]},"is_claimable":false,"name":"Prolonged Time-to-antihypertensive Therapy Worsens Organ Damage and Blood Pressure Control in Arterial Hypertension.","description":"<h4>Introduction</h4>Delay in arterial hypertension (AH) diagnosis and late therapy initiation may affect progression towards hypertensive-mediated organ damage (HMOD) and blood pressure (BP) control.<h4>Aim</h4>We aimed to assess the impact of time-to-therapy on BP control and HMOD in patients receiving AH diagnosis.<h4>Methods</h4>We analysed data from the Campania Salute Network, a prospective registry of hypertensive patients (NCT02211365). At baseline visit, time-to-therapy was defined as the interval between the first occurrence of BP values exceeding guidelines-directed thresholds and therapy initiation; HMOD included left ventricular hypertrophy (LVH), carotid plaque, or chronic kidney disease. Optimal BP control was considered for average values < 140/90 mmHg. Low-risk profile was","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Nov","modification":"2026-06-03T05:28:11.886Z","creation":"2025-04-04T01:57:45.572Z"},"accession":"S-EPMC11604795","cross_references":{"pubmed":["39369129"],"doi":["10.1007/s40292-024-00673-x"]}}