biostudies-literatureUnknown31(6)Lembo MUniversità degli Studi di Napoli Federico II<h4>Introduction</h4>Delay in arterial hypertension (AH) diagnosis and late therapy initiation may affect progression towards hypertensive-mediated organ damage (HMOD) and blood pressure (BP) control.<h4>Aim</h4>We aimed to assess the impact of time-to-therapy on BP control and HMOD in patients receiving AH diagnosis.<h4>Methods</h4>We analysed data from the Campania Salute Network, a prospective registry of hypertensive patients (NCT02211365). At baseline visit, time-to-therapy was defined as the interval between the first occurrence of BP values exceeding guidelines-directed thresholds and therapy initiation; HMOD included left ventricular hypertrophy (LVH), carotid plaque, or chronic kidney disease. Optimal BP control was considered for average values < 140/90 mmHg. Low-risk profile wasHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension639-648https://www.ebi.ac.uk/biostudies/studies/S-EPMC11604795biostudies-literatureProlonged Time-to-antihypertensive Therapy Worsens Organ Damage and Blood Pressure Control in Arterial Hypertension.PMC11604795Morisco CPacella DPiccolo RMancusi CLembo MCanciello GTrimarco BBardi LManzi MVLosi MACarnevale DEsposito GIzzo RGiugliano GBossone EfalseProlonged Time-to-antihypertensive Therapy Worsens Organ Damage and Blood Pressure Control in Arterial Hypertension.<h4>Introduction</h4>Delay in arterial hypertension (AH) diagnosis and late therapy initiation may affect progression towards hypertensive-mediated organ damage (HMOD) and blood pressure (BP) control.<h4>Aim</h4>We aimed to assess the impact of time-to-therapy on BP control and HMOD in patients receiving AH diagnosis.<h4>Methods</h4>We analysed data from the Campania Salute Network, a prospective registry of hypertensive patients (NCT02211365). At baseline visit, time-to-therapy was defined as the interval between the first occurrence of BP values exceeding guidelines-directed thresholds and therapy initiation; HMOD included left ventricular hypertrophy (LVH), carotid plaque, or chronic kidney disease. Optimal BP control was considered for average values < 140/90 mmHg. Low-risk profile was2024-01-01T00:00:00Z2024 Nov2026-06-03T05:28:11.886Z2025-04-04T01:57:45.572ZS-EPMC116047953936912910.1007/s40292-024-00673-x