{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Campbell-Salome G"],"funding":["NHLBI NIH HHS","National Institutes of Health","National Heart Lung and Blood Institute"],"pagination":["e832-e843"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11606789"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["18(5)"],"pubmed_abstract":["<h4>Background</h4>Cascade testing can be highly effective in identifying individuals with familial hypercholesterolemia (FH) and help prevent atherosclerotic cardiovascular disease. The IMPACT-FH cascade testing program offered multiple optimized implementation strategies to improve FH cascade testing uptake.<h4>Objective</h4>Guided by the Conceptual Model of Implementation Research, this study assessed the IMPACT-FH cascade testing program's implementation outcomes.<h4>Methods</h4>Implementation outcomes were assessed qualitatively and quantitatively. Interviews were conducted with 33 IMPACT-FH program participants including 15 probands, 12 relatives, and 6 healthcare professionals (HCPs). Transcripts were analyzed using thematic analysis to investigate implementation outcomes. Descripti"],"journal":["Journal of clinical lipidology"],"pubmed_title":["Utilizing innovative implementation strategies for familial hypercholesterolemia: Implementation outcomes from the IMPACT-FH study."],"pmcid":["PMC11606789"],"funding_grant_id":["R01HL148246","R01 HL148246"],"pubmed_authors":["Sturm AC","McGowan MP","Walters NL","Morgan KM","Rahm AK","Tricou EP","Jones LK","Campbell-Salome G","Brangan A","Gabriel J"],"additional_accession":[]},"is_claimable":false,"name":"Utilizing innovative implementation strategies for familial hypercholesterolemia: Implementation outcomes from the IMPACT-FH study.","description":"<h4>Background</h4>Cascade testing can be highly effective in identifying individuals with familial hypercholesterolemia (FH) and help prevent atherosclerotic cardiovascular disease. The IMPACT-FH cascade testing program offered multiple optimized implementation strategies to improve FH cascade testing uptake.<h4>Objective</h4>Guided by the Conceptual Model of Implementation Research, this study assessed the IMPACT-FH cascade testing program's implementation outcomes.<h4>Methods</h4>Implementation outcomes were assessed qualitatively and quantitatively. Interviews were conducted with 33 IMPACT-FH program participants including 15 probands, 12 relatives, and 6 healthcare professionals (HCPs). Transcripts were analyzed using thematic analysis to investigate implementation outcomes. Descripti","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Sep-Oct","modification":"2026-05-29T07:04:58.448Z","creation":"2026-04-08T03:52:05.527Z"},"accession":"S-EPMC11606789","cross_references":{"pubmed":["39278768"],"doi":["10.1016/j.jacl.2024.07.011"]}}