biostudies-literatureWeiss PFNational Institute of Arthritis and Musculoskeletal and Skin DiseasesIntramural NIH HHSNIAMS NIH HHS1797-1808https://www.ebi.ac.uk/biostudies/studies/S-EPMC11606790biostudies-literatureUnknown76(12)<h4>Objective</h4>The goal was to develop and validate classification criteria for axial juvenile spondyloarthritis (SpA; AxJSpA).<h4>Methods</h4>This international initiative consisted of four phases: (1) item generation, (2) item reduction, (3) criteria development, and (4) validation of the AxJSpA criteria by an independent team of experts in an internationally representative validation cohort.<h4>Results</h4>These criteria are intended to be used on youth with a physician diagnosis of juvenile SpA and for whom axial disease is suspected. Item generation consisted of a systematic literature review and a free-listing exercise using input from international physicians, which collectively resulted in 108 items. After the item reduction exercise and expert panel input, 37 items remained forArthritis & rheumatology (Hoboken, N.J.)Classification Criteria for Axial Disease in Youth With Juvenile Spondyloarthritis.PMC11606790R01 AR0732011R01AR074098AR041184R01 AR074098R01AR073201ZIA AR041184P30AR070253P30 AR070253Maksymowych WPMinden KWeiss PFKlein-Gitelman MSTse SMStoll MLNaden RColbert RAKasapcopur OOzen SHorneff GBrandon TGRavelli AHendry AMLovell DJSmith JABiko DMJaremko JLFrancavilla MLHerregods NVan den Bosch FRuperto NFoeldvari ILambert RGNigrovic PAJoos RYildiz MLaxer RMBurgos-Vargas RAggarwal AChauvin NASrinivasalu HfalseClassification Criteria for Axial Disease in Youth With Juvenile Spondyloarthritis.<h4>Objective</h4>The goal was to develop and validate classification criteria for axial juvenile spondyloarthritis (SpA; AxJSpA).<h4>Methods</h4>This international initiative consisted of four phases: (1) item generation, (2) item reduction, (3) criteria development, and (4) validation of the AxJSpA criteria by an independent team of experts in an internationally representative validation cohort.<h4>Results</h4>These criteria are intended to be used on youth with a physician diagnosis of juvenile SpA and for whom axial disease is suspected. Item generation consisted of a systematic literature review and a free-listing exercise using input from international physicians, which collectively resulted in 108 items. After the item reduction exercise and expert panel input, 37 items remained for2024-01-01T00:00:00Z2024 Dec2026-06-06T07:22:03.518Z2026-06-06T03:07:22.368ZS-EPMC116067903903989910.1002/art.42959