biostudies-literatureUnknown15Zhu Z<h4>Background</h4>Triphala, is a composite of three individual botanical drugs: <i>Terminalia chebula</i>, <i>Terminalia bellirica</i>, and <i>Emblica officinalis</i>. It exhibits properties such as heatclearing, anti-inflammatory, anti-fatigue, antioxidant, and antibacterial effects,making it extensively utilized in India and Tibet. It has been found to exhibitinhibitory effects on <i>Helicobacter pylori</i> (<i>H. pylori</i>); however, further comprehensive research is still needed to elucidate its specific antibacterial mechanism. The present study investigates the in vitro antibacterial activity and antibacterial mechanism of Triphala against <i>H. pylori</i>.<h4>Methods</h4>Ours research investigates the <i>in vitro</i> inhibitory activity of Triphala on multiple standard and clinicaFrontiers in pharmacology1438193https://www.ebi.ac.uk/biostudies/studies/S-EPMC11611552biostudies-literaturePreliminary investigation of the <i>in vitro</i> anti-<i>Helicobacter pylori</i> activity of Triphala.PMC11611552Zhang GLi HSu BZhu ZFeng ZChen MYao MHao YZhang LPang YJia JZou YLai YWei ROu LfalsePreliminary investigation of the <i>in vitro</i> anti-<i>Helicobacter pylori</i> activity of Triphala.<h4>Background</h4>Triphala, is a composite of three individual botanical drugs: <i>Terminalia chebula</i>, <i>Terminalia bellirica</i>, and <i>Emblica officinalis</i>. It exhibits properties such as heatclearing, anti-inflammatory, anti-fatigue, antioxidant, and antibacterial effects,making it extensively utilized in India and Tibet. It has been found to exhibitinhibitory effects on <i>Helicobacter pylori</i> (<i>H. pylori</i>); however, further comprehensive research is still needed to elucidate its specific antibacterial mechanism. The present study investigates the in vitro antibacterial activity and antibacterial mechanism of Triphala against <i>H. pylori</i>.<h4>Methods</h4>Ours research investigates the <i>in vitro</i> inhibitory activity of Triphala on multiple standard and clinica2024-01-01T00:00:00Z20242026-04-08T19:49:58.087Z2025-04-06T00:33:01.012ZS-EPMC116115523962907510.3389/fphar.2024.1438193