biostudies-literatureUnknown170(3)Katzendobler SKlinikum der Universität München<h4>Background</h4>Survival times of patients with IDH-mutant gliomas are variable and can extend to decades. Many studies provide progression-free rather than overall survival times and prognostic factors remain ill-defined. Here we explored characteristics of short- and long-term survivors within a cohort of patients with extended follow-up.<h4>Methods</h4>This single-center, case-control study included 86 patients diagnosed between 1998 and 2023 who either died within 6 years after diagnosis or survived at least 15 years. Patient characteristics and prognostic factors were stratified by short- (< 6 years) versus long-term (≥ 15 years) survival.<h4>Results</h4>Forty-seven patients (55%) diagnosed with astrocytoma and 39 patients (45%) with oligodendroglioma were included retrospectively.Journal of neuro-oncology655-664https://www.ebi.ac.uk/biostudies/studies/S-EPMC11614945biostudies-literatureDeterminants of long-term survival in patients with IDH-mutant gliomas.PMC11614945Weller MThon Nvon Baumgarten LBlobner JKatzendobler SNiedermeyer SHarter PNTonn JCStoecklein VMTrumm CWeller JfalseDeterminants of long-term survival in patients with IDH-mutant gliomas.<h4>Background</h4>Survival times of patients with IDH-mutant gliomas are variable and can extend to decades. Many studies provide progression-free rather than overall survival times and prognostic factors remain ill-defined. Here we explored characteristics of short- and long-term survivors within a cohort of patients with extended follow-up.<h4>Methods</h4>This single-center, case-control study included 86 patients diagnosed between 1998 and 2023 who either died within 6 years after diagnosis or survived at least 15 years. Patient characteristics and prognostic factors were stratified by short- (< 6 years) versus long-term (≥ 15 years) survival.<h4>Results</h4>Forty-seven patients (55%) diagnosed with astrocytoma and 39 patients (45%) with oligodendroglioma were included retrospectively.2024-01-01T00:00:00Z2024 Dec2026-06-03T03:17:02.747Z2025-04-04T01:23:41.848ZS-EPMC116149453931631610.1007/s11060-024-04826-9