{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9"],"submitter":["Cao N"],"pubmed_abstract":["<h4>Backgrounds</h4>Coronary microvascular obstruction (MVO) frequently occurs in patients with ST-segment elevation myocardial infarction (STEMI) following percutaneous coronary intervention (PCI), leading to poor prognosis. β<sub>1</sub> adrenergic receptor autoantibodies (β<sub>1</sub>-AA) are present in various cardiovascular diseases and correlate with cardiac damage and dysfunction. However, whether β<sub>1</sub>-AA is associated with the occurrence of MVO in patients with STEMI after PCI remains unclear.<h4>Aims</h4>To investigate the prognostic relationship between β<sub>1</sub>-AA and the occurrence of MVO in patients with STEMI with post-PCI.<h4>Methods</h4>This prospective study included 403 patients with STEMI who underwent primary PCI. The patients were divided into MVO+ and M"],"journal":["Journal of translational autoimmunity"],"pagination":["100261"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11615580"],"repository":["biostudies-literature"],"pubmed_title":["Prognostic value of β1 adrenergic receptor autoantibodies for microvascular obstruction in patients with STEMI with Post-PCI: A prospective cohort study."],"pmcid":["PMC11615580"],"pubmed_authors":["Cao N","Li J","Li S","Li Q","Guo S","Chen H","Dang W","Xin Y"],"additional_accession":[]},"is_claimable":false,"name":"Prognostic value of β1 adrenergic receptor autoantibodies for microvascular obstruction in patients with STEMI with Post-PCI: A prospective cohort study.","description":"<h4>Backgrounds</h4>Coronary microvascular obstruction (MVO) frequently occurs in patients with ST-segment elevation myocardial infarction (STEMI) following percutaneous coronary intervention (PCI), leading to poor prognosis. β<sub>1</sub> adrenergic receptor autoantibodies (β<sub>1</sub>-AA) are present in various cardiovascular diseases and correlate with cardiac damage and dysfunction. However, whether β<sub>1</sub>-AA is associated with the occurrence of MVO in patients with STEMI after PCI remains unclear.<h4>Aims</h4>To investigate the prognostic relationship between β<sub>1</sub>-AA and the occurrence of MVO in patients with STEMI with post-PCI.<h4>Methods</h4>This prospective study included 403 patients with STEMI who underwent primary PCI. The patients were divided into MVO+ and M","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2026-06-02T22:08:16.164Z","creation":"2025-04-04T01:56:59.341Z"},"accession":"S-EPMC11615580","cross_references":{"pubmed":["39634465"],"doi":["10.1016/j.jtauto.2024.100261"]}}