biostudies-literatureUnknown9Cao N<h4>Backgrounds</h4>Coronary microvascular obstruction (MVO) frequently occurs in patients with ST-segment elevation myocardial infarction (STEMI) following percutaneous coronary intervention (PCI), leading to poor prognosis. β₁ adrenergic receptor autoantibodies (β₁-AA) are present in various cardiovascular diseases and correlate with cardiac damage and dysfunction. However, whether β₁-AA is associated with the occurrence of MVO in patients with STEMI after PCI remains unclear.<h4>Aims</h4>To investigate the prognostic relationship between β₁-AA and the occurrence of MVO in patients with STEMI with post-PCI.<h4>Methods</h4>This prospective study included 403 patients with STEMI who underwent primary PCI. The patients were divided into MVO+ and MJournal of translational autoimmunity100261https://www.ebi.ac.uk/biostudies/studies/S-EPMC11615580biostudies-literaturePrognostic value of β1 adrenergic receptor autoantibodies for microvascular obstruction in patients with STEMI with Post-PCI: A prospective cohort study.PMC11615580Cao NLi JLi SLi QGuo SChen HDang WXin YfalsePrognostic value of β1 adrenergic receptor autoantibodies for microvascular obstruction in patients with STEMI with Post-PCI: A prospective cohort study.<h4>Backgrounds</h4>Coronary microvascular obstruction (MVO) frequently occurs in patients with ST-segment elevation myocardial infarction (STEMI) following percutaneous coronary intervention (PCI), leading to poor prognosis. β₁ adrenergic receptor autoantibodies (β₁-AA) are present in various cardiovascular diseases and correlate with cardiac damage and dysfunction. However, whether β₁-AA is associated with the occurrence of MVO in patients with STEMI after PCI remains unclear.<h4>Aims</h4>To investigate the prognostic relationship between β₁-AA and the occurrence of MVO in patients with STEMI with post-PCI.<h4>Methods</h4>This prospective study included 403 patients with STEMI who underwent primary PCI. The patients were divided into MVO+ and M2024-01-01T00:00:00Z2024 Dec2026-06-02T22:08:16.164Z2025-04-04T01:56:59.341ZS-EPMC116155803963446510.1016/j.jtauto.2024.100261