biostudies-literatureUnknown19Hu TDelivery and weaning are major stressful events in sows and piglets, adversely affecting production and growth performance and causing economic losses to swine farms. Probiotics as safe antibiotic alternatives have great potential for use across all stages of livestock farming. Here, 18 pregnant sows from clinical farms randomly were divided into two groups: one fed a basal diet (CON group) and the other fed a basal diet plus a probiotic mixture CBB-mix (containing 1×10¹² CFU/g of <i>Lactobacillus johnsonii</i> [CJ21], 1×10⁹ CFU/g of <i>Bacillus subtilis</i> [BS15], and 1×10⁹ CFU/g of <i>Bacillus licheniformis</i> [BL21]), for 20 days before delivery. The effects of maternal CBB-mix supplementation on sow colostrum metabolome and offspring piglets' clinicalAnimal nutrition (Zhongguo xu mu shou yi xue hui)386-400https://www.ebi.ac.uk/biostudies/studies/S-EPMC11617873biostudies-literatureMaternal probiotic mixture supplementation optimizes the gut microbiota structure of offspring piglets through the gut-breast axis.PMC11617873Yang GHu TXie FYang LChen KZhu YWang JSong ZWu YfalseMaternal probiotic mixture supplementation optimizes the gut microbiota structure of offspring piglets through the gut-breast axis.Delivery and weaning are major stressful events in sows and piglets, adversely affecting production and growth performance and causing economic losses to swine farms. Probiotics as safe antibiotic alternatives have great potential for use across all stages of livestock farming. Here, 18 pregnant sows from clinical farms randomly were divided into two groups: one fed a basal diet (CON group) and the other fed a basal diet plus a probiotic mixture CBB-mix (containing 1×10¹² CFU/g of <i>Lactobacillus johnsonii</i> [CJ21], 1×10⁹ CFU/g of <i>Bacillus subtilis</i> [BS15], and 1×10⁹ CFU/g of <i>Bacillus licheniformis</i> [BL21]), for 20 days before delivery. The effects of maternal CBB-mix supplementation on sow colostrum metabolome and offspring piglets' clinical2024-01-01T00:00:00Z2024 Dec2025-04-04T01:15:29.227Z2025-04-04T01:15:29.227ZS-EPMC116178733964054910.1016/j.aninu.2024.04.025