{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yang LY"],"funding":["NIGMS NIH HHS"],"pagination":["288"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11618342"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(1)"],"pubmed_abstract":["Lipid-protein interactions are crucial for virtually all biological processes in living cells. However, existing structural databases focusing on these interactions are limited to integral membrane proteins. A systematic understanding of diverse lipid-protein interactions also encompassing lipid-anchored, peripheral membrane and soluble lipid binding proteins remains to be elucidated. To address this gap and facilitate the research of universal lipid-protein assemblies, we developed BioDolphin - a curated database with over 127,000 lipid-protein interactions. BioDolphin provides comprehensive annotations, including protein functions, protein families, lipid classifications, lipid-protein binding affinities, membrane association type, and atomic structures. Accessible via a publicly availab"],"journal":["Communications chemistry"],"pubmed_title":["BioDolphin as a comprehensive database of lipid-protein binding interactions."],"pmcid":["PMC11618342"],"funding_grant_id":["R35 GM150890"],"pubmed_authors":["Yang LY","Ping K","Luo Y","McShan AC"],"additional_accession":[]},"is_claimable":false,"name":"BioDolphin as a comprehensive database of lipid-protein binding interactions.","description":"Lipid-protein interactions are crucial for virtually all biological processes in living cells. However, existing structural databases focusing on these interactions are limited to integral membrane proteins. A systematic understanding of diverse lipid-protein interactions also encompassing lipid-anchored, peripheral membrane and soluble lipid binding proteins remains to be elucidated. To address this gap and facilitate the research of universal lipid-protein assemblies, we developed BioDolphin - a curated database with over 127,000 lipid-protein interactions. BioDolphin provides comprehensive annotations, including protein functions, protein families, lipid classifications, lipid-protein binding affinities, membrane association type, and atomic structures. Accessible via a publicly availab","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2026-06-01T20:40:06.423Z","creation":"2025-04-06T17:31:13.041Z"},"accession":"S-EPMC11618342","cross_references":{"pubmed":["39633021"],"doi":["10.1038/s42004-024-01384-z"]}}