{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["52(5)"],"submitter":["Dinsa Guta R"],"funding":["Institute of Planning and Evaluation for Technology in Food, Agriculture and Forestry"],"pubmed_abstract":["<i>Pseudoperonospora cubensis</i> is a significant phytopathogen causing downy mildew disease in cucurbit crops. Understanding the molecular mechanisms underlying the interaction between <i>P. cubensis</i> and its host is essential for developing effective disease management strategies. RxLR effectors, secreted by pathogens, play a crucial role in modulating host immunity. In this study, we sequenced the genome of the <i>P. cubensis</i> isolate CNU-OTH and identified RxLR effector genes using bioinformatics tools. A total of 45 RxLR effector genes were identified from the genome of <i>P. cubensis</i>. Cloning and functional characterization of these effectors were performed through transient expression assays in <i>Nicotiana benthamiana</i> leaves. Subcellular localization of selected effe"],"journal":["Mycobiology"],"pagination":["306-316"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11619035"],"repository":["biostudies-literature"],"pubmed_title":["Identification of <i>Pseudoperonospora cubensis</i> RxLR Effector Genes <i>via</i> Genome Sequencing."],"pmcid":["PMC11619035"],"pubmed_authors":["Jeong I","Semunyana M","Min J","Arif S","Kim SH","Dinsa Guta R","Oh SK"],"additional_accession":[]},"is_claimable":false,"name":"Identification of <i>Pseudoperonospora cubensis</i> RxLR Effector Genes <i>via</i> Genome Sequencing.","description":"<i>Pseudoperonospora cubensis</i> is a significant phytopathogen causing downy mildew disease in cucurbit crops. Understanding the molecular mechanisms underlying the interaction between <i>P. cubensis</i> and its host is essential for developing effective disease management strategies. RxLR effectors, secreted by pathogens, play a crucial role in modulating host immunity. In this study, we sequenced the genome of the <i>P. cubensis</i> isolate CNU-OTH and identified RxLR effector genes using bioinformatics tools. A total of 45 RxLR effector genes were identified from the genome of <i>P. cubensis</i>. Cloning and functional characterization of these effectors were performed through transient expression assays in <i>Nicotiana benthamiana</i> leaves. Subcellular localization of selected effe","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024","modification":"2026-05-26T20:12:47.56Z","creation":"2025-04-19T14:37:42.27Z"},"accession":"S-EPMC11619035","cross_references":{"pubmed":["39649145"],"doi":["10.1080/12298093.2024.2408064"]}}