{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang S"],"funding":["NCI NIH HHS"],"pagination":["eads1584"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11627201"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["10(49)"],"pubmed_abstract":["Computed tomography (CT) scanners are essential for modern imaging but require around 600 projections from various angles. We present x-ray-induced acoustic computed tomography (XACT), a method that uses radiation-induced acoustic waves for three-dimensional (3D) x-ray imaging. These spherical acoustic waves travel through tissue at 1.5 × 10<sup>3</sup> meters per second, much slower than x-rays, allowing ultrasound detectors to capture them and generate 3D images without mechanical scanning. We validate this theory by performing 3D numerical reconstructions of a human breast from a single x-ray projection and experimentally determining 3D structures of objects at different depths. Achieving resolutions of 0.4 millimeters in the <i>XZ</i> plane and 3.5 millimeters in the <i>XY</i> plane at"],"journal":["Science advances"],"pubmed_title":["X-ray-induced acoustic computed tomography: 3D X-ray absorption imaging from a single view."],"pmcid":["PMC11627201"],"funding_grant_id":["R50 CA283816","P30 CA062203","U01 CA288351","R37 CA240806"],"pubmed_authors":["Sun L","Wang S","Pandey PK","Lee G","Xiang L","van Bergen RJP","Xu Y"],"additional_accession":[]},"is_claimable":false,"name":"X-ray-induced acoustic computed tomography: 3D X-ray absorption imaging from a single view.","description":"Computed tomography (CT) scanners are essential for modern imaging but require around 600 projections from various angles. We present x-ray-induced acoustic computed tomography (XACT), a method that uses radiation-induced acoustic waves for three-dimensional (3D) x-ray imaging. These spherical acoustic waves travel through tissue at 1.5 × 10<sup>3</sup> meters per second, much slower than x-rays, allowing ultrasound detectors to capture them and generate 3D images without mechanical scanning. We validate this theory by performing 3D numerical reconstructions of a human breast from a single x-ray projection and experimentally determining 3D structures of objects at different depths. Achieving resolutions of 0.4 millimeters in the <i>XZ</i> plane and 3.5 millimeters in the <i>XY</i> plane at","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2025-04-03T23:56:15.327Z","creation":"2025-04-03T23:56:15.327Z"},"accession":"S-EPMC11627201","cross_references":{"pubmed":["39642225"],"doi":["10.1126/sciadv.ads1584"]}}