{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Escudero M"],"funding":["The Swiss National Science Foundations","Swiss National Science Foundation","The Spanish Ministry of Science and Innovation","José Castillejo Program, Spanish Ministry of Education and Professional Training","Max-Planck-Gesellschaft"],"pagination":["e17086"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11628656"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["33(24)"],"pubmed_abstract":["Holocentric organisms, unlike typical monocentric organisms, have kinetochore activity distributed along almost the whole length of the chromosome. Because of this, chromosome rearrangements through fission and fusion are more likely to become fixed in holocentric species, which may account for the extraordinary rates of chromosome evolution that many holocentric lineages exhibit. Long blocks of genome synteny have been reported in animals with holocentric chromosomes despite high rates of chromosome rearrangements. Nothing is known from plants, however, despite the fact that holocentricity appears to have played a key role in the diversification of one of the largest angiosperm genera, Carex (Cyperaceae). In the current study, we compared genomes of Carex species and a distantly related C"],"journal":["Molecular ecology"],"pubmed_title":["Genomic hotspots of chromosome rearrangements explain conserved synteny despite high rates of chromosome evolution in a holocentric lineage."],"pmcid":["PMC11628656"],"funding_grant_id":["CAS19/00294","202869","PCEFP3_202869","REPRODRAD PGC2018-099608-B-100","DiversiChrom PID2021-122715NB-I00"],"pubmed_authors":["Marques A","Hipp AL","Lucek K","Escudero M"],"additional_accession":[]},"is_claimable":false,"name":"Genomic hotspots of chromosome rearrangements explain conserved synteny despite high rates of chromosome evolution in a holocentric lineage.","description":"Holocentric organisms, unlike typical monocentric organisms, have kinetochore activity distributed along almost the whole length of the chromosome. Because of this, chromosome rearrangements through fission and fusion are more likely to become fixed in holocentric species, which may account for the extraordinary rates of chromosome evolution that many holocentric lineages exhibit. Long blocks of genome synteny have been reported in animals with holocentric chromosomes despite high rates of chromosome rearrangements. Nothing is known from plants, however, despite the fact that holocentricity appears to have played a key role in the diversification of one of the largest angiosperm genera, Carex (Cyperaceae). In the current study, we compared genomes of Carex species and a distantly related C","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2026-06-01T20:36:06.792Z","creation":"2025-04-04T02:33:44.543Z"},"accession":"S-EPMC11628656","cross_references":{"pubmed":["37486041"],"doi":["10.1111/mec.17086"]}}