{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Abu-Elmakarem H"],"funding":["US National Science foundation","Gordon and Betty Moore Foundation","Czech Science Foundation"],"pagination":["evae262"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11635102"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16(12)"],"pubmed_abstract":["The early evolution of eukaryotes and their adaptations to low-oxygen environments are fascinating open questions in biology. Genome-scale data from novel eukaryotes, and particularly from free-living lineages, are the key to answering these questions. The Parabasalia are a major group of anaerobic eukaryotes that form the most speciose lineage of Metamonada. The most well-studied are parasitic parabasalids, including Trichomonas vaginalis and Tritrichomonas foetus, but very little genome-scale data are available for free-living members of the group. Here, we sequenced the transcriptome of Pseudotrichomonas keilini, a free-living parabasalian. Comparative genomic analysis indicated that P. keilini possesses a metabolism and gene complement that are in many respects similar to its parasitic"],"journal":["Genome biology and evolution"],"pubmed_title":["Transcriptome and Evolutionary Analysis of Pseudotrichomonas keilini, a Free-Living Anaerobic Eukaryote."],"pmcid":["PMC11635102"],"funding_grant_id":["DEB-2045329","GBMF9741","22-22538S"],"pubmed_authors":["Gile GH","Taerum SJ","Williams TA","Petitjean C","Kotyk M","Kay C","Cepicka I","Abu-Elmakarem H","Bass D"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptome and Evolutionary Analysis of Pseudotrichomonas keilini, a Free-Living Anaerobic Eukaryote.","description":"The early evolution of eukaryotes and their adaptations to low-oxygen environments are fascinating open questions in biology. Genome-scale data from novel eukaryotes, and particularly from free-living lineages, are the key to answering these questions. The Parabasalia are a major group of anaerobic eukaryotes that form the most speciose lineage of Metamonada. The most well-studied are parasitic parabasalids, including Trichomonas vaginalis and Tritrichomonas foetus, but very little genome-scale data are available for free-living members of the group. Here, we sequenced the transcriptome of Pseudotrichomonas keilini, a free-living parabasalian. Comparative genomic analysis indicated that P. keilini possesses a metabolism and gene complement that are in many respects similar to its parasitic","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2026-06-03T00:46:41.726Z","creation":"2025-04-05T09:28:29.932Z"},"accession":"S-EPMC11635102","cross_references":{"pubmed":["39656733"],"doi":["10.1093/gbe/evae262"]}}