biostudies-literaturePage CENational Cancer InstituteNCI NIH HHS64-73https://www.ebi.ac.uk/biostudies/studies/S-EPMC11636615biostudies-literatureUnknown170<h4>Objective</h4>The menopause transition is associated with difficulties in executive function. However, it is unclear whether these difficulties persist past perimenopause. This study investigated whether potential confounders, including natural vs. surgical postmenopause and menopause-related psychological symptoms, influence whether executive dysfunction persists into postmenopause.<h4>Study design</h4>A cross-sectional sample of women aged 35-65 years (N = 1971) in one of four groups, premenopause, perimenopause, natural postmenopause, and surgical postmenopause, were surveyed. Participants self-reported executive functioning with the Brown Attention Deficit Disorder Scale (BADDS), anxiety symptom severity with the Generalized Anxiety Disorder Questionnaire (GAD-7), and depression syMaturitasNatural vs. surgical postmenopause and psychological symptoms confound the effect of menopause on executive functioning domains of cognitive experience.PMC11636615R01 CA215587Page CEDuffy KAMetcalf CAEpperson CNSoreth BLoughead JSammel MDJohnson RLfalseNatural vs. surgical postmenopause and psychological symptoms confound the effect of menopause on executive functioning domains of cognitive experience.<h4>Objective</h4>The menopause transition is associated with difficulties in executive function. However, it is unclear whether these difficulties persist past perimenopause. This study investigated whether potential confounders, including natural vs. surgical postmenopause and menopause-related psychological symptoms, influence whether executive dysfunction persists into postmenopause.<h4>Study design</h4>A cross-sectional sample of women aged 35-65 years (N = 1971) in one of four groups, premenopause, perimenopause, natural postmenopause, and surgical postmenopause, were surveyed. Participants self-reported executive functioning with the Brown Attention Deficit Disorder Scale (BADDS), anxiety symptom severity with the Generalized Anxiety Disorder Questionnaire (GAD-7), and depression sy2023-01-01T00:00:00Z2023 Apr2025-04-04T01:20:44.675Z2025-04-04T01:20:44.675ZS-EPMC116366153680693110.1016/j.maturitas.2023.01.007