{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Walters MK"],"funding":["NICHD NIH HHS","NIAID NIH HHS","Wellcome Trust"],"pubmed_abstract":["<h4>Background</h4>Eliminating HIV vertical transmission (VT) is a global priority and monitored by estimating paediatric HIV infections with the Joint United Nations Programme on HIV/AIDS supported Spectrum AIDS Impact Module (Spectrum-AIM). Recent innovations in antiretroviral therapy (ART) service delivery models and first-line regimens aimed to reduce VT probabilities. We conducted a systematic review and meta-analysis to estimate VT probabilities by maternal immunologic and treatment status.<h4>Methods</h4>We combined an updated systematic review with previous data in meta-regression models to estimate VT probabilities and determinants. We searched multiple databases for peer-reviewed English-language studies from all regions published between January 2018 and February 2024 with VT da"],"journal":["medRxiv : the preprint server for health sciences"],"pagination":["2024.12.03.24318418"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11643157"],"repository":["biostudies-literature"],"pubmed_title":["Probability of vertical HIV transmission: A systematic review and meta-regression."],"pmcid":["PMC11643157"],"funding_grant_id":["T32 AI007140","R01 AI152721","F31 HD116617"],"pubmed_authors":["Walters MK","Sabin M","Imai-Eaton JW","Hicks S","Glaubius R","Stover J","Richey A","Kyu H","Powis K","Barry M","Boily MC","Bulterys MA","Louden D","Mahy M","Mofenson L"],"additional_accession":[]},"is_claimable":false,"name":"Probability of vertical HIV transmission: A systematic review and meta-regression.","description":"<h4>Background</h4>Eliminating HIV vertical transmission (VT) is a global priority and monitored by estimating paediatric HIV infections with the Joint United Nations Programme on HIV/AIDS supported Spectrum AIDS Impact Module (Spectrum-AIM). Recent innovations in antiretroviral therapy (ART) service delivery models and first-line regimens aimed to reduce VT probabilities. We conducted a systematic review and meta-analysis to estimate VT probabilities by maternal immunologic and treatment status.<h4>Methods</h4>We combined an updated systematic review with previous data in meta-regression models to estimate VT probabilities and determinants. We searched multiple databases for peer-reviewed English-language studies from all regions published between January 2018 and February 2024 with VT da","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Apr","modification":"2025-08-14T03:05:36.679Z","creation":"2025-08-14T03:05:36.679Z"},"accession":"S-EPMC11643157","cross_references":{"pubmed":["39677422"],"doi":["10.1101/2024.12.03.24318418"]}}