{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Aglipay M"],"funding":["Canadian Immunity Task Force","CIHR"],"pagination":["913-923"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11644124"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["115(6)"],"pubmed_abstract":["<h4>Objective</h4>Characterizing the seroprevalence of SARS-CoV-2 antibodies in children is needed to optimize the COVID-19 public health response. We quantified the seroprevalence of SARS-CoV-2 infection-acquired antibodies and vaccine-acquired antibodies among children receiving primary care in Toronto, Canada.<h4>Methods</h4>We conducted a longitudinal cohort study between January 2021 and November 2022 in healthy children aged 0-16 years receiving primary care in Toronto. The primary and secondary outcomes were seroprevalence of SARS-COV-2 infection-acquired antibodies and vaccine-acquired antibodies ascertained from finger-prick dried blood spots. Samples were tested using an enzyme-linked immunosorbent assay for antibodies to full-length spike trimer and nucleocapsid. We explored soc"],"journal":["Canadian journal of public health = Revue canadienne de sante publique"],"pubmed_title":["Seroprevalence of SARS-CoV-2 antibodies among children receiving primary care in Toronto, Ontario."],"pmcid":["PMC11644124"],"funding_grant_id":["468613"],"pubmed_authors":["Tursun T","Persaud N","Malick A","Clark J","Durocher Y","Young E","Begum EA","Maguire J","Tuite A","Nasser S","Rodrigues M","Porepa M","Abraham E","Owen J","Stewart K","Jansz G","Ying E","Lakhanpal G","Taylor C","Sgro M","Grewal K","Raso P","Guiang C","Craig A","Knowles H","Parkin P","Chan J","Hanson L","Raza D","Socynska I","Shepherd S","Do A","Yaremko J","Anderson LN","Jacobson S","Mailhot G","Assan R","Nash K","Lebovic G","Kwok B","De Guerra V","Arafeh D","Stern D","Bondar H","Weir S","Stitt A","Bustos M","Reid-Westoby C","Rhodes M","Saunderson J","Zaccaria M","Qi V","Offord A","Kim J","Constantin E","Gazeley S","Moodie R","Djolovic A","Ogwuru M","Carsley S","D'Hollander C","Pabon T","Gringas AC","Calpin C","Harrington L","Freeman S","De Castris-Garcia K","Li A","Yoshida-Montezuma Y","Kelleher S","Derocher MB","Lakhoo S","Turner S","Egger A","Siam F","Kandel R","Jagiello L","Zajdman M","Cheng E","Wong P","van den Heuvel M","Mitchell M","Kadar P","Arbess G","Colwill K","Marquez S","Allen C","Peer M","Baker J","Qi F","Jaleel M","Birken C","Tavares ES","Cost K","Gingras AC","Vanderhout S","Shuja H","Vanderloo L","Doukas K","Mamdani M","Colford M","Fuller A","Skelding J","Lahiry P","Bonifacio J","Thompson J","Shin J","Nnorom IS","Srikanthan C","Lam-Antoniades M","Thorpe K","Schiralli V","Janus M","Treherne S","Shaibu H","Leung FH","Ruderman C","Keiswetter L","Keown-Stoneman C","Li P","Freedman A","Li X","Farber A","Pinto A","Garcia A","Weisdorf T","TARGet Kids! Collaboration","Cheema S","Mok E","Kiran T","Dharman S","Meret A","Delgado-Brand M","Danayan K","Barozzino T","Das P","Handford C","Perlmutar M","Bowry A","Kurt K","Kwong JC","Omand JA","McFarlane NL","Ramji N","Borkhoff CM","Flores PR","Ha D","Rouleau K","Bloch G","Thadani S","Uddin F","Salsa R","Duku E","Aglipay M","Anderson K","Male R","Bayoumi I","Kinlin L","Campbell D","Thompson L","Ali S","Leduc D","Lau E","Batten J","Juni P","Bergeron S","Chisamore B"],"additional_accession":[]},"is_claimable":false,"name":"Seroprevalence of SARS-CoV-2 antibodies among children receiving primary care in Toronto, Ontario.","description":"<h4>Objective</h4>Characterizing the seroprevalence of SARS-CoV-2 antibodies in children is needed to optimize the COVID-19 public health response. We quantified the seroprevalence of SARS-CoV-2 infection-acquired antibodies and vaccine-acquired antibodies among children receiving primary care in Toronto, Canada.<h4>Methods</h4>We conducted a longitudinal cohort study between January 2021 and November 2022 in healthy children aged 0-16 years receiving primary care in Toronto. The primary and secondary outcomes were seroprevalence of SARS-COV-2 infection-acquired antibodies and vaccine-acquired antibodies ascertained from finger-prick dried blood spots. Samples were tested using an enzyme-linked immunosorbent assay for antibodies to full-length spike trimer and nucleocapsid. We explored soc","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2026-05-13T16:08:07.442Z","creation":"2026-04-27T03:08:39.126Z"},"accession":"S-EPMC11644124","cross_references":{"pubmed":["39168962"],"doi":["10.17269/s41997-024-00916-3"]}}