{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["64(4)"],"submitter":["Zuraik AA"],"pubmed_abstract":["An intricate relationship exists, and interactions occur between the gut microbiota and colorectal cancer (CRC). Recent studies have indicated that inflammatory reactions stimulated by <i>Fusobacterium nucleatum</i> (<i>Fn</i>) lead to the development of CRC. Radical surgery combined with adjuvant chemotherapy is the primary treatment approach for most CRC patients. This study was designed to evaluate the abundance of <i>Fn</i> as part of the gut microbiota in patients with CRC compared to healthy individuals and to assess the effect of the gut microbiota <i>Fn</i> on patients undergoing adjuvant chemotherapy and those experiencing CRC relapse. There were 201 participants, comprising 50 healthy controls and 151 CRC patients. Stool samples were collected from three CRC groups (postoperative"],"journal":["Indian journal of microbiology"],"pagination":["1938-1950"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11645352"],"repository":["biostudies-literature"],"pubmed_title":["Effect of Chemotherapy on &lt;i&gt;Fusobacterium nucleatum&lt;/i&gt; Abundance in Colorectal Cancer Patients: A Study on Relapsing Patients."],"pmcid":["PMC11645352"],"pubmed_authors":["Daboul Y","Awama MA","Kayasseh MA","Zuraik AA","Georges M","Yazigi H"],"additional_accession":[]},"is_claimable":false,"name":"Effect of Chemotherapy on &lt;i&gt;Fusobacterium nucleatum&lt;/i&gt; Abundance in Colorectal Cancer Patients: A Study on Relapsing Patients.","description":"An intricate relationship exists, and interactions occur between the gut microbiota and colorectal cancer (CRC). Recent studies have indicated that inflammatory reactions stimulated by <i>Fusobacterium nucleatum</i> (<i>Fn</i>) lead to the development of CRC. Radical surgery combined with adjuvant chemotherapy is the primary treatment approach for most CRC patients. This study was designed to evaluate the abundance of <i>Fn</i> as part of the gut microbiota in patients with CRC compared to healthy individuals and to assess the effect of the gut microbiota <i>Fn</i> on patients undergoing adjuvant chemotherapy and those experiencing CRC relapse. There were 201 participants, comprising 50 healthy controls and 151 CRC patients. Stool samples were collected from three CRC groups (postoperative","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2026-06-14T03:13:23.793Z","creation":"2026-06-14T03:08:39.24Z"},"accession":"S-EPMC11645352","cross_references":{"pubmed":["39678992"],"doi":["10.1007/s12088-024-01279-6"]}}