biostudies-literatureUnknown64(4)Zuraik AAAn intricate relationship exists, and interactions occur between the gut microbiota and colorectal cancer (CRC). Recent studies have indicated that inflammatory reactions stimulated by <i>Fusobacterium nucleatum</i> (<i>Fn</i>) lead to the development of CRC. Radical surgery combined with adjuvant chemotherapy is the primary treatment approach for most CRC patients. This study was designed to evaluate the abundance of <i>Fn</i> as part of the gut microbiota in patients with CRC compared to healthy individuals and to assess the effect of the gut microbiota <i>Fn</i> on patients undergoing adjuvant chemotherapy and those experiencing CRC relapse. There were 201 participants, comprising 50 healthy controls and 151 CRC patients. Stool samples were collected from three CRC groups (postoperativeIndian journal of microbiology1938-1950https://www.ebi.ac.uk/biostudies/studies/S-EPMC11645352biostudies-literatureEffect of Chemotherapy on <i>Fusobacterium nucleatum</i> Abundance in Colorectal Cancer Patients: A Study on Relapsing Patients.PMC11645352Daboul YAwama MAKayasseh MAZuraik AAGeorges MYazigi HfalseEffect of Chemotherapy on <i>Fusobacterium nucleatum</i> Abundance in Colorectal Cancer Patients: A Study on Relapsing Patients.An intricate relationship exists, and interactions occur between the gut microbiota and colorectal cancer (CRC). Recent studies have indicated that inflammatory reactions stimulated by <i>Fusobacterium nucleatum</i> (<i>Fn</i>) lead to the development of CRC. Radical surgery combined with adjuvant chemotherapy is the primary treatment approach for most CRC patients. This study was designed to evaluate the abundance of <i>Fn</i> as part of the gut microbiota in patients with CRC compared to healthy individuals and to assess the effect of the gut microbiota <i>Fn</i> on patients undergoing adjuvant chemotherapy and those experiencing CRC relapse. There were 201 participants, comprising 50 healthy controls and 151 CRC patients. Stool samples were collected from three CRC groups (postoperative2024-01-01T00:00:00Z2024 Dec2026-06-14T03:13:23.793Z2026-06-14T03:08:39.24ZS-EPMC116453523967899210.1007/s12088-024-01279-6