{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["61(1)"],"submitter":["Alcicek S"],"funding":["Else Kröner-Fresenius-Stiftung (EKFS)","Deutsche Krebshilfe","Mildred Scheel Career Center Frankfurt (Deutsche Krebshilfe)","Else Kröner-Fresenius-Stiftung","LOEWE grant within the CePTER Consortium"],"pubmed_abstract":["<h4>Background</h4>Emerging evidence suggests that fasting could play a key role in cancer treatment. Its metabolic effects on gliomas require further investigation.<h4>Purpose</h4>To design a multi-voxel <sup>1</sup>H/<sup>31</sup>P MR-spectroscopic imaging (MRSI) protocol for noninvasive metabolic monitoring of cerebral, fasting-induced changes on an individual patient/tumor level, and to assess its technical reliability/reproducibility.<h4>Study type</h4>Prospective.<h4>Population</h4>MRS phantom. Twenty-two patients (mean age = 61, 6 female) with suspected WHO grade II-IV glioma examined before and after 72-hour-fasting prior to biopsy/resection.<h4>Field strength/sequence</h4>3-T, <sup>1</sup>H decoupled 3D <sup>31</sup>P MRSI, 2D <sup>1</sup>H sLASER MRSI at an echo time of 144 msec,"],"journal":["Journal of magnetic resonance imaging : JMRI"],"pagination":["426-438"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11645487"],"repository":["biostudies-literature"],"pubmed_title":["2D <sup>1</sup>H sLASER Long-TE and 3D <sup>31</sup>P Chemical Shift Imaging at 3 T for Monitoring Fasting-Induced Changes in Brain Tumor Tissue."],"pmcid":["PMC11645487"],"pubmed_authors":["Ronellenfitsch MW","Weber KJ","Dive I","Thomas DC","Pilatus U","Wenger KJ","Czabanka M","Steinbach JP","Hattingen E","Forster MT","Alcicek S","Prinz V"],"additional_accession":[]},"is_claimable":false,"name":"2D <sup>1</sup>H sLASER Long-TE and 3D <sup>31</sup>P Chemical Shift Imaging at 3 T for Monitoring Fasting-Induced Changes in Brain Tumor Tissue.","description":"<h4>Background</h4>Emerging evidence suggests that fasting could play a key role in cancer treatment. Its metabolic effects on gliomas require further investigation.<h4>Purpose</h4>To design a multi-voxel <sup>1</sup>H/<sup>31</sup>P MR-spectroscopic imaging (MRSI) protocol for noninvasive metabolic monitoring of cerebral, fasting-induced changes on an individual patient/tumor level, and to assess its technical reliability/reproducibility.<h4>Study type</h4>Prospective.<h4>Population</h4>MRS phantom. Twenty-two patients (mean age = 61, 6 female) with suspected WHO grade II-IV glioma examined before and after 72-hour-fasting prior to biopsy/resection.<h4>Field strength/sequence</h4>3-T, <sup>1</sup>H decoupled 3D <sup>31</sup>P MRSI, 2D <sup>1</sup>H sLASER MRSI at an echo time of 144 msec,","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jan","modification":"2026-07-15T08:13:16.635Z","creation":"2025-04-04T01:54:58.019Z"},"accession":"S-EPMC11645487","cross_references":{"pubmed":["38722043"],"doi":["10.1002/jmri.29422"]}}