{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(1)"],"submitter":["Nelissen KJ"],"pubmed_abstract":["<h4>Purpose</h4>In postoperative breast irradiation, changes in the breast contour and arm positioning can result in patient positioning errors and offline replanning. This can lead to increased treatment burden and strain on departmental logistics because of the need for additional cone beam computed tomography (CBCT) images or even a new radiation therapy treatment plan (TP). Online daily adaptive radiation therapy (oART) could provide a solution to these challenges. We have clinically implemented and evaluated the feasibility of oART for whole breast irradiation.<h4>Methods and materials</h4>Twenty patients treated with postoperative whole breast right irradiation (5 × 5.2 Gy) were included in BREAST-ART, a prospective single-arm trial. The dosimetry of the reference TP calculated on th"],"journal":["Advances in radiation oncology"],"pagination":["101664"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11647482"],"repository":["biostudies-literature"],"pubmed_title":["Clinical Implementation of Cone Beam Computed Tomography-Guided Online Adaptive Radiation Therapy in Whole Breast Irradiation."],"pmcid":["PMC11647482"],"pubmed_authors":["Slotman BJ","BREAST-ART study group","Middelburg-van Rijn JG","Goudschaal KN","Nelissen KJ","Admiraal MA","van Vlaenderen ARW","van der Himst J","Rijksen BLT","Verbakel WFAR","van den Bongard DHJG","Visser J","Bucko E"],"additional_accession":[]},"is_claimable":false,"name":"Clinical Implementation of Cone Beam Computed Tomography-Guided Online Adaptive Radiation Therapy in Whole Breast Irradiation.","description":"<h4>Purpose</h4>In postoperative breast irradiation, changes in the breast contour and arm positioning can result in patient positioning errors and offline replanning. This can lead to increased treatment burden and strain on departmental logistics because of the need for additional cone beam computed tomography (CBCT) images or even a new radiation therapy treatment plan (TP). Online daily adaptive radiation therapy (oART) could provide a solution to these challenges. We have clinically implemented and evaluated the feasibility of oART for whole breast irradiation.<h4>Methods and materials</h4>Twenty patients treated with postoperative whole breast right irradiation (5 × 5.2 Gy) were included in BREAST-ART, a prospective single-arm trial. The dosimetry of the reference TP calculated on th","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Jan","modification":"2026-06-01T12:11:57.194Z","creation":"2025-04-06T22:14:02.218Z"},"accession":"S-EPMC11647482","cross_references":{"pubmed":["39687477"],"doi":["10.1016/j.adro.2024.101664"]}}