{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"submitter":["Kendler KS"],"pubmed_abstract":["<h4>Background</h4>Drug use Disorder (DUD), the risk for which is substantially influenced by both genetic and social factors, is geographically concentrated in high-risk regions. An important step toward understanding this pattern is to examine geographical distributions of the genetic liability to DUD and a key demographic risk factor - social deprivation.<h4>Methods</h4>We calculated the mean family genetic risk score (FGRS) for DUD ((FGRS<sub>DUD</sub>) and social deprivation for each of the 5983 areas Demographic Statistical Areas (DeSO) for all of Sweden and used geospatial techniques to analyze and map these factors.<h4>Results</h4>Using 2018 data, substantial spatial heterogeneity was seen in the distribution of the genetic risk for DUD in Sweden as a whole and in its three major u"],"journal":["Psychological medicine"],"pagination":["1-10"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11650187"],"repository":["biostudies-literature"],"pubmed_title":["The geographical distribution of the family-genetic risk score for drug use disorder in Sweden and its co-localization with areas of social deprivation."],"pmcid":["PMC11650187"],"pubmed_authors":["Sundquist J","Stewart K","Sundquist K","Ohlsson H","Malmberg B","Zhao P","Mansourian A","Kendler KS"],"additional_accession":[]},"is_claimable":false,"name":"The geographical distribution of the family-genetic risk score for drug use disorder in Sweden and its co-localization with areas of social deprivation.","description":"<h4>Background</h4>Drug use Disorder (DUD), the risk for which is substantially influenced by both genetic and social factors, is geographically concentrated in high-risk regions. An important step toward understanding this pattern is to examine geographical distributions of the genetic liability to DUD and a key demographic risk factor - social deprivation.<h4>Methods</h4>We calculated the mean family genetic risk score (FGRS) for DUD ((FGRS<sub>DUD</sub>) and social deprivation for each of the 5983 areas Demographic Statistical Areas (DeSO) for all of Sweden and used geospatial techniques to analyze and map these factors.<h4>Results</h4>Using 2018 data, substantial spatial heterogeneity was seen in the distribution of the genetic risk for DUD in Sweden as a whole and in its three major u","dates":{"release":"2024-01-01T00:00:00Z","publication":"2024 Dec","modification":"2025-04-18T14:21:24.163Z","creation":"2025-04-04T21:44:55.379Z"},"accession":"S-EPMC11650187","cross_references":{"pubmed":["39618330"],"doi":["10.1017/S0033291724002745"]}}