biostudies-literatureAdam ABill and Melinda Gates Foundation4030-4039https://www.ebi.ac.uk/biostudies/studies/S-EPMC11650653biostudies-literatureUnknown10(12)The coronavirus pandemic outbreak of 2019 highlighted the critical importance of preparedness for current and future public health threats (https://www.mmv.org/mmv-open/global-health-priority-box/about-global-health-priority-box). While the main attention for the past few years has been on COVID-19 research, this focus has reduced global resources on research in other areas, including malaria and neglected tropical diseases (NTDs). Such a shift in focus puts at risk the hard-earned progress in global health achieved over the past two decades (https://www.who.int/news-room/spotlight/10-global-health-issues-to-track-in-2021). To address the urgent need for new drugs to combat drug-resistant malaria, emerging zoonotic diseases, and vector control, Medicines for Malaria Venture (MMV) and InnovACS infectious diseasesGlobal Health Priority Box─Proactive Pandemic Preparedness.PMC11650653INV-007155Norton LHawryluk NBurrows JNHooft van Huisjduijnen RBryant RLaleu BAdam ABesson DWillis PASamby KKCanan SRees SPalmer MRobinson DfalseGlobal Health Priority Box─Proactive Pandemic Preparedness.The coronavirus pandemic outbreak of 2019 highlighted the critical importance of preparedness for current and future public health threats (https://www.mmv.org/mmv-open/global-health-priority-box/about-global-health-priority-box). While the main attention for the past few years has been on COVID-19 research, this focus has reduced global resources on research in other areas, including malaria and neglected tropical diseases (NTDs). Such a shift in focus puts at risk the hard-earned progress in global health achieved over the past two decades (https://www.who.int/news-room/spotlight/10-global-health-issues-to-track-in-2021). To address the urgent need for new drugs to combat drug-resistant malaria, emerging zoonotic diseases, and vector control, Medicines for Malaria Venture (MMV) and Innov2024-01-01T00:00:00Z2024 Dec2025-04-04T01:08:57.532Z2025-04-04T01:08:57.532ZS-EPMC116506533948874610.1021/acsinfecdis.4c00700