biostudies-literatureWang YPioneer Talent Recruitment Program ( Category B), Chinese Academy of SciencesKey Research and Development Program of Jiangxi ProvinceNational Natural Science Foundation of ChinaScience and Technology Agency of Henan ProvinceNational Key Research and Development Program of Chinae2407051https://www.ebi.ac.uk/biostudies/studies/S-EPMC11653596biostudies-literatureUnknown11(47)Advancing and deploying Fenton-inactive Cd that combines excellent catalytic activity, selectivity, and stability remains a serious challenge, predominantly owing to the difficulty in regulating the intrinsic electronic states and local geometric structures of such fully occupied d¹⁰s² configuration. In this work, a combination of experiments and theoretical calculations reveals that the incorporation of boron (B) enables the tuning of the average oxidation state of Cd⁰ to Cd^δ+, facilitating electron localization and implementing a different electrocatalytic preference compared to conventional d¹⁰-electron configurations. The resulting Cd(B) catalyst demonstrates high selectivity (>90% on average) in the O₂-to-H₂OAdvanced science (Weinheim, Baden-Wurttemberg, Germany)Fenton-Inactive Cd Enables Highly Selective O<sub>2</sub>-Derived Domino Reaction.PMC11653596E425C0022020YFE02045002170204522210224012020243BBG71021grants 21401203Deng RYang YHao ZLiu QSong SWang HWang YDong QYou HfalseFenton-Inactive Cd Enables Highly Selective O<sub>2</sub>-Derived Domino Reaction.Advancing and deploying Fenton-inactive Cd that combines excellent catalytic activity, selectivity, and stability remains a serious challenge, predominantly owing to the difficulty in regulating the intrinsic electronic states and local geometric structures of such fully occupied d¹⁰s² configuration. In this work, a combination of experiments and theoretical calculations reveals that the incorporation of boron (B) enables the tuning of the average oxidation state of Cd⁰ to Cd^δ+, facilitating electron localization and implementing a different electrocatalytic preference compared to conventional d¹⁰-electron configurations. The resulting Cd(B) catalyst demonstrates high selectivity (>90% on average) in the O₂-to-H₂O2024-01-01T00:00:00Z2024 Dec2025-04-27T00:31:47.101Z2025-04-06T17:52:05.839ZS-EPMC116535963951340910.1002/advs.202407051