{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["57(1)"],"submitter":["Chen Y"],"pubmed_abstract":["<h4>Background</h4>Accumulating evidence has demonstrated that the long non-coding RNA (lncRNA) lymphocytic leukaemia deletion gene 1 (DLEU1) is abnormally overexpressed in many cancer types, including cervical cancer (CC). However, the potential clinical significance of DLEU1 in serum exosomes of patients with CC remains unclear.<h4>Methods</h4>The expression of serum exosomal DLEU1 was detected by quantitative real-time polymerase chain reaction (qRT-PCR). A receiver operating characteristic (ROC) curve was plotted to evaluate the clinical diagnostic efficacy of DLEU1. The Kaplan-Meier survival curve and Cox proportional hazards model were used to assess the effect of DLEU1 on postoperative recurrence, metastasis and prognosis among patients with CC.<h4>Results</h4>Our research showed th"],"journal":["Annals of medicine"],"pagination":["2442537"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC11654034"],"repository":["biostudies-literature"],"pubmed_title":["The expression and clinical significance of serum exosomal-long non-coding RNA DLEU1 in patients with cervical cancer."],"pmcid":["PMC11654034"],"pubmed_authors":["Zhao W","Xia Q","Chen Y","Cui F","Wu X"],"additional_accession":[]},"is_claimable":false,"name":"The expression and clinical significance of serum exosomal-long non-coding RNA DLEU1 in patients with cervical cancer.","description":"<h4>Background</h4>Accumulating evidence has demonstrated that the long non-coding RNA (lncRNA) lymphocytic leukaemia deletion gene 1 (DLEU1) is abnormally overexpressed in many cancer types, including cervical cancer (CC). However, the potential clinical significance of DLEU1 in serum exosomes of patients with CC remains unclear.<h4>Methods</h4>The expression of serum exosomal DLEU1 was detected by quantitative real-time polymerase chain reaction (qRT-PCR). A receiver operating characteristic (ROC) curve was plotted to evaluate the clinical diagnostic efficacy of DLEU1. The Kaplan-Meier survival curve and Cox proportional hazards model were used to assess the effect of DLEU1 on postoperative recurrence, metastasis and prognosis among patients with CC.<h4>Results</h4>Our research showed th","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2025-04-26T17:00:16.518Z","creation":"2025-04-06T15:24:39.817Z"},"accession":"S-EPMC11654034","cross_references":{"pubmed":["39687982"],"doi":["10.1080/07853890.2024.2442537"]}}