biostudies-literatureUnknown28(1)Schreiber N<h4>Introduction</h4>Delirium is a frequent complication in critically ill patients and is associated with adverse outcomes such as long-term cognitive impairment and increased mortality. It is unknown whether there are sex-related differences in intensive care unit (ICU) delirium and associated outcomes. We aimed to assess sex-specific differences in short-term mortality following ICU-delirium.<h4>Methods</h4>We conducted a retrospective cohort study using the Medical Information Mart for Intensive Care-IV (MIMIC-IV) database. Adult ICU patients who were diagnosed with delirium using the Confusion Assessment Method for the ICU (CAM-ICU) were included. The primary outcome was 30-day mortality following delirium onset. To control for baseline differences in demographics, illness severity, aCritical care (London, England)413https://www.ebi.ac.uk/biostudies/studies/S-EPMC11654059biostudies-literatureSex specific differences in short-term mortality after ICU-delirium.PMC11654059Eichinger MScholz LEichlseder MBaumgartner JFandler-Hofler SOrlob SKlivinyi CSchorghuber MEller PSchreiber NPichler AZoidl PfalseSex specific differences in short-term mortality after ICU-delirium.<h4>Introduction</h4>Delirium is a frequent complication in critically ill patients and is associated with adverse outcomes such as long-term cognitive impairment and increased mortality. It is unknown whether there are sex-related differences in intensive care unit (ICU) delirium and associated outcomes. We aimed to assess sex-specific differences in short-term mortality following ICU-delirium.<h4>Methods</h4>We conducted a retrospective cohort study using the Medical Information Mart for Intensive Care-IV (MIMIC-IV) database. Adult ICU patients who were diagnosed with delirium using the Confusion Assessment Method for the ICU (CAM-ICU) were included. The primary outcome was 30-day mortality following delirium onset. To control for baseline differences in demographics, illness severity, a2024-01-01T00:00:00Z2024 Dec2025-04-04T01:50:53.44Z2025-04-04T01:50:53.44ZS-EPMC116540593969569810.1186/s13054-024-05204-7